STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpf31U4/U6 small nuclear ribonucleoprotein Prp31; Involved in pre-mRNA splicing as component of the spliceosome. Required for the assembly of the U4/U5/U6 tri-snRNP complex, one of the building blocks of the spliceosome. (508 aa)    
Predicted Functional Partners:
prpf4
PRP4 pre-mRNA-processing factor 4 homolog (yeast).
   
 0.999
snrnp200
Small nuclear ribonucleoprotein 200 (U5).
    
 
 0.999
prpf3
PRP3 pre-mRNA-processing factor 3 homolog (yeast).
   
 0.999
prpf8
Pre-mRNA-processing factor 8.
   
 
 0.999
prpf6
PRP6 pre-mRNA-processing factor 6 homolog (S. cerevisiae).
   
 0.999
sart1
Spliceosome-associated factor 1, recruiter of U4/U6.U5 tri-snRNP.
   
 0.998
eftud2
Elongation factor Tu GTP-binding domain-containing 2.
   
 0.998
lsm8
U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.
    
 0.998
lsm6
LSM6 homolog, U6 small nuclear RNA and mRNA degradation-associated.
    
 0.994
mfap1
Microfibril-associated protein 1.
   
 
 0.993
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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