STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxo10F-box protein 10. (1015 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1A; Belongs to the SKP1 family.
    
 0.792
cul1a
Cullin 1a; Belongs to the cullin family.
   
 0.765
sp100.3
SP110 nuclear body protein, tandem duplicate 3.
      
 0.670
nae1
NEDD8-activating enzyme E1 regulatory subunit; Regulatory subunit of the dimeric uba3-nae1 E1 enzyme. E1 activates nedd8 by first adenylating its C-terminal glycine residue with ATP, thereafter linking this residue to the side chain of the catalytic cysteine, yielding a nedd8-uba3 thioester and free AMP. E1 finally transfers nedd8 to the catalytic cysteine of ube2m (By similarity); Belongs to the ubiquitin-activating E1 family. ULA1 subfamily.
    
 0.580
cul1b
Cullin 1b; Belongs to the cullin family.
   
 
 0.578
cand1
Cullin-associated and neddylation-dissociated 1.
   
 
 0.573
fbxw5
F-box and WD repeat domain-containing 5.
     
 0.563
fbxl16
F-box and leucine-rich repeat protein 16.
     
 0.558
frmpd1b
FERM and PDZ domain-containing 1b.
      
 0.528
fbxw2
F-box and WD repeat domain-containing 2.
   
 
 0.525
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.