node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
buc | meig1 | ENSDARP00000125536 | ENSDARP00000121928 | Bucky ball; Prion-like protein required for the formation of Balbiani body (electron-dense aggregates in the oocyte) and germ plasm assembly, and for the establishment of oocyte polarity during early oogenesis. Mobility and aggregation properties are improved by tudor domain-containing protein tdrd6 through interaction with dimethylated arginines Tri-RG domains. Establishes oocyte polarity through interactions with RNA-binding proteins rbpms2 and dazl, initiating a positive feedback loop amplification mechanism in the Balbiani body. Interaction of BUC protein and mRNA with rbpms2 and d [...] | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.744 |
buc | morn3 | ENSDARP00000125536 | ENSDARP00000029276 | Bucky ball; Prion-like protein required for the formation of Balbiani body (electron-dense aggregates in the oocyte) and germ plasm assembly, and for the establishment of oocyte polarity during early oogenesis. Mobility and aggregation properties are improved by tudor domain-containing protein tdrd6 through interaction with dimethylated arginines Tri-RG domains. Establishes oocyte polarity through interactions with RNA-binding proteins rbpms2 and dazl, initiating a positive feedback loop amplification mechanism in the Balbiani body. Interaction of BUC protein and mRNA with rbpms2 and d [...] | MORN repeat-containing 3. | 0.548 |
buc | nanos3 | ENSDARP00000125536 | ENSDARP00000089386 | Bucky ball; Prion-like protein required for the formation of Balbiani body (electron-dense aggregates in the oocyte) and germ plasm assembly, and for the establishment of oocyte polarity during early oogenesis. Mobility and aggregation properties are improved by tudor domain-containing protein tdrd6 through interaction with dimethylated arginines Tri-RG domains. Establishes oocyte polarity through interactions with RNA-binding proteins rbpms2 and dazl, initiating a positive feedback loop amplification mechanism in the Balbiani body. Interaction of BUC protein and mRNA with rbpms2 and d [...] | Nanos homolog 3; Belongs to the nanos family. | 0.839 |
ccdc114 | dync2li1 | ENSDARP00000013307 | ENSDARP00000058146 | Coiled-coil domain-containing 114. | Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. | 0.429 |
ccdc114 | meig1 | ENSDARP00000013307 | ENSDARP00000121928 | Coiled-coil domain-containing 114. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.740 |
ccdc114 | pacrg | ENSDARP00000013307 | ENSDARP00000106202 | Coiled-coil domain-containing 114. | PARK2 co-regulated. | 0.622 |
ccdc114 | ropn1l | ENSDARP00000013307 | ENSDARP00000123631 | Coiled-coil domain-containing 114. | Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.574 |
ccdc114 | tekt2 | ENSDARP00000013307 | ENSDARP00000059357 | Coiled-coil domain-containing 114. | Tektin 2 (testicular). | 0.737 |
dync2li1 | ccdc114 | ENSDARP00000058146 | ENSDARP00000013307 | Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. | Coiled-coil domain-containing 114. | 0.429 |
dync2li1 | meig1 | ENSDARP00000058146 | ENSDARP00000121928 | Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | 0.441 |
meig1 | buc | ENSDARP00000121928 | ENSDARP00000125536 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Bucky ball; Prion-like protein required for the formation of Balbiani body (electron-dense aggregates in the oocyte) and germ plasm assembly, and for the establishment of oocyte polarity during early oogenesis. Mobility and aggregation properties are improved by tudor domain-containing protein tdrd6 through interaction with dimethylated arginines Tri-RG domains. Establishes oocyte polarity through interactions with RNA-binding proteins rbpms2 and dazl, initiating a positive feedback loop amplification mechanism in the Balbiani body. Interaction of BUC protein and mRNA with rbpms2 and d [...] | 0.744 |
meig1 | ccdc114 | ENSDARP00000121928 | ENSDARP00000013307 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Coiled-coil domain-containing 114. | 0.740 |
meig1 | dync2li1 | ENSDARP00000121928 | ENSDARP00000058146 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Cytoplasmic dynein 2 light intermediate chain 1; Required for correct intraflagellar transport (IFT), the bi- directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. | 0.441 |
meig1 | morn3 | ENSDARP00000121928 | ENSDARP00000029276 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | MORN repeat-containing 3. | 0.444 |
meig1 | nanos3 | ENSDARP00000121928 | ENSDARP00000089386 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Nanos homolog 3; Belongs to the nanos family. | 0.630 |
meig1 | pacrg | ENSDARP00000121928 | ENSDARP00000106202 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | PARK2 co-regulated. | 0.927 |
meig1 | ropn1l | ENSDARP00000121928 | ENSDARP00000123631 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Ropporin-1-like protein; Important for male fertility. With ROPN1, involved in fibrous sheath integrity and sperm motility, plays a role in PKA-dependent signaling processes required for spermatozoa capacitation. Belongs to the ropporin family. | 0.697 |
meig1 | spag6 | ENSDARP00000121928 | ENSDARP00000023131 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Sperm-associated antigen 6. | 0.673 |
meig1 | tekt2 | ENSDARP00000121928 | ENSDARP00000059357 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Tektin 2 (testicular). | 0.871 |
meig1 | wee2 | ENSDARP00000121928 | ENSDARP00000109848 | Meiosis expressed gene 1 protein homolog; Essential for spermiogenesis. | Wee1-like protein kinase 2; Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits cdk1 and acts as a key regulator of meiosis. Required to maintain meiotic arrest in oocytes by phosphorylating cdk1 at 'Tyr-15', leading to inhibit cdk1 activity and prevent meiotic reentry (By similarity); Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. WEE1 subfamily. | 0.807 |