STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kctd15aBTB/POZ domain-containing protein kctd15-like. (257 aa)    
Predicted Functional Partners:
ube2ia
SUMO-conjugating enzyme UBC9-B; Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4. Essential for nuclear architecture and chromosome segregation (By similarity). Mediates nuclear localization of vsx1. Required for progression through mitosis during organogenesis. Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.807
tfap2a
Transcription factor AP-2 alpha.
   
 
 0.717
krt222
Keratin 222; Belongs to the intermediate filament family.
      
 0.696
ube2ib
SUMO-conjugating enzyme UBC9-A; Accepts the ubiquitin-like proteins sumo1, sumo2 and sumo3 from the uble1a-uble1b E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as ranbp2 or cbx4. Essential for nuclear architecture and chromosome segregation (By similarity). Mediates nuclear localization of vsx1. Required for progression through mitosis during organogenesis. Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.689
ccdc174
Coiled-coil domain-containing 174.
   
  
 0.664
tnnt2d
Troponin T2d, cardiac.
      
 0.664
kctd2
Potassium channel tetramerization domain-containing 2.
    
 
0.586
ednrab
Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family.
      
 0.581
kcnj1a.1
Potassium inwardly rectifying channel subfamily J member 1a, tandem duplicate 1.
      
 0.565
tfap2c
Transcription factor AP-2 gamma (activating enhancer-binding protein 2 gamma).
   
 
 0.479
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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