STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fam184aFamily with sequence similarity 184 member A. (1145 aa)    
Predicted Functional Partners:
nwd2
NACHT and WD repeat domain-containing 2.
    
 
 0.872
cadps2
Ca++-dependent secretion activator 2.
      
 0.719
faf1
Fas (TNFRSF6)-associated factor 1.
      
 0.646
kbtbd8
Kelch repeat and BTB domain-containing protein 8; Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex that acts as a regulator of neural crest specification (By similarity). The BCR(KBTBD8) complex acts by mediating monoubiquitination of target proteins (By similarity).
      
 0.453
prickle3
Prickle homolog 3.
    
 
 0.452
fbxo42
F-box protein 42.
    
 
 0.430
ckap5
Cytoskeleton-associated protein 5.
    
 
 0.402
lrrk2
Leucine-rich repeat kinase 2.
    
 
 0.400
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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