STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fam174bMembrane protein FAM174B; Essential for Golgi structural integrity. Belongs to the FAM174 family. (143 aa)    
Predicted Functional Partners:
nudt8
Nudix (nucleoside diphosphate-linked moiety X)-type motif 8.
      
 0.870
pdxp
Pyridoxal (pyridoxine, vitamin B6) phosphatase; Belongs to the HAD-like hydrolase superfamily.
      
 0.841
tbc1d16
TBC1 domain family, member 16.
      
 0.800
mad1l1
Mitotic arrest deficient-like protein 1.
      
 0.744
mfsd12a
Major facilitator superfamily domain-containing 12a.
      
 0.742
lysmd4
LysM and putative peptidoglycan-binding domain-containing protein 4.
      
 0.695
slc44a5a
Choline transporter-like protein 5-A.
   
  
 0.669
tspan2a
Tetraspanin.
   
  
 0.649
cxadr
Coxsackievirus and adenovirus receptor homolog; May function as a homophilic cell adhesion molecule and be essential for tight junction integrity. May also be involved in transepithelial migration of leukocytes through adhesive interactions with jaml. The interaction between both receptors may also mediate the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair (By similarity).
      
 0.645
vps51
Vacuolar protein sorting-associated protein 51 homolog; Involved in retrograde transport from early and late endosomes to the late Golgi. The GARP complex is required for the maintenance of protein retrieval from endosomes to the TGN, acid hydrolase sorting, lysosome function, endosomal cholesterol traffic and autophagy. Acts as component of the EARP complex that is involved in endocytic recycling (By similarity).
      
 0.619
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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