STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
elk3ETS transcription factor ELK3. (408 aa)    
Predicted Functional Partners:
gtf2e2
Transcription initiation factor IIE subunit beta; Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH. Both TFIIH and TFIIE are required for promoter clearance by RNA polymerase.
      
 0.664
tlk1a
Tousled-like kinase 1a.
      
 0.660
srfa
Serum response factor a.
   
 
 0.570
srfb
Serum response factor b.
    
 
 0.567
zbtb18
Zinc finger and BTB domain-containing protein 18; Transcriptional repressor that plays a role in various developmental processes. Specifically binds the consensus DNA sequence 5'-[AC]ACATCTG[GT][AC]-3' which contains the E box core, and acts by recruiting chromatin remodeling multiprotein complexes (By similarity). Belongs to the krueppel C2H2-type zinc-finger protein family. ZBTB18 subfamily.
      
 0.562
npas1
Neuronal PAS domain protein 1.
   
 
 0.512
ets1
V-ets avian erythroblastosis virus E26 oncogene homolog 1.
   
  
 0.506
chd9
Chromodomain helicase DNA-binding protein 9.
    
 
 0.482
elf1
E74-like ETS transcription factor 1.
   
 
0.481
nme2b.1
Nucleoside diphosphate kinase.
    
 
 0.480
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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