STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cfap300Cilia and flagella-associated protein 300. (272 aa)    
Predicted Functional Partners:
Dnaaf5
TOG domain-containing protein.
    
 
 0.877
cfap298
Cilia- and flagella-associated protein 298; Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly. Seems to be important for initiation rather than maintenance of cilium motility. Required for correct positioning of cilia at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway. May suppress canonical Wnt signaling activity ; Belongs to the CFAP298 family.
    
 
 0.876
pih1d3
PIH1 domain-containing 3.
   
 
 0.843
ttc12
Tetratricopeptide repeat domain 12.
   
 
 0.831
spag1a
Sperm-associated antigen 1A; May play a role in the cytoplasmic assembly and/or trafficking of the axonemal dynein arms.
    
 
 0.825
pih1d2
PIH1 domain-containing protein 2; Belongs to the PIH1 family.
   
 
 0.801
wdr92
WD repeat-containing protein 92; Seems to act as a modulator of apoptosis.
   
 
 0.763
dnaaf1
Dynein assembly factor 1, axonemal; Cilium-specific protein required for the stability of the ciliary architecture. Involved in regulation of microtubule-based cilia and actin-based brush border microvilli (Probable).
   
 
 0.692
dnali1
Dynein, axonemal, light intermediate chain 1.
   
  
 0.655
dnaaf3
Dynein assembly factor 3, axonemal; Required for the assembly of axonemal inner and outer dynein arms. Involved in preassembly of dyneins into complexes before their transport into cilia; Belongs to the DNAAF3 family.
      
 0.638
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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