STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
calr3bCalreticulin. (417 aa)    
Predicted Functional Partners:
pdia3
Protein disulfide-isomerase.
   
 0.997
hsp90b1
Heat shock protein 90, beta (Grp94), member 1.
   
 
 0.982
pdia7
Protein disulfide-isomerase.
   
 0.974
pdia8
Protein disulfide-isomerase.
   
 0.962
calr
Calreticulin.
  
 
0.955
calr3a
Calreticulin.
  
  
0.951
mhc1zba
MHC class I antigen ZBA transcript variant 1; Belongs to the MHC class I family.
   
 
 0.928
hspa5
Immunoglobulin binding protein; Belongs to the heat shock protein 70 family.
   
 
 0.889
hyou1
Hypoxia up-regulated protein 1; Has a pivotal role in cytoprotective cellular mechanisms triggered by oxygen deprivation. May play a role as a molecular chaperone and participate in protein folding; Belongs to the heat shock protein 70 family.
   
 
 0.872
pdia6
Protein disulfide isomerase family A, member 6; Belongs to the protein disulfide isomerase family.
   
 
 0.866
Your Current Organism:
Danio rerio
NCBI taxonomy Id: 7955
Other names: Brachydanio rerio, Brachydanio rerio frankei, Cyprinus rerio, D. rerio, Danio frankei, Danio rerio frankei, leopard danio, zebra danio, zebra fish, zebrafish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.