STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptsPPhosphoenolpyruvate-protein phosphotransferase of PTS system (enzyme I); General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (583 aa)    
Predicted Functional Partners:
MW7_0286
Phosphotransferase system, phosphocarrier protein HPr; Protein involved in sugar:hydrogen symporter activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
 
 0.999
ptsN
Protein involved in sugar:hydrogen symporter activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
 
 
 0.932
MW7_0285
Pts system fructose iia component (phosphoenolpyruvate-dependent sugar phosphotransferase system); Protein involved in protein-N(PI)-phosphohistidine-sugar phosphotransferase activity and phosphoenolpyruvate-dependent sugar phosphotransferase system.
 
   
 0.857
hprK
Hpr(ser) kinase / phosphatase; Catalyzes the ATP- as well as the pyrophosphate-dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P-Ser-HPr).
 
   
 0.856
eno
Enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
  
 
 0.768
MW7_1865
Transketolase; Protein involved in oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor and metabolic process.
 
 
 0.746
pgi
Protein involved in glucose-6-phosphate isomerase activity and starch metabolic process; Belongs to the GPI family.
  
 
 0.702
tuf
Protein involved in translation elongation factor activity and regulation of translational elongation.
   
    0.682
MW7_2216
Pyruvate-flavodoxin oxidoreductase PorG; Protein involved in thiamin pyrophosphate binding and oxidation reduction.
     
 0.663
pyk
Pyruvate kinase; Protein involved in magnesium ion binding and gluconeogenesis; Belongs to the pyruvate kinase family.
   
 
 0.654
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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