node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
MW7_1236 | MW7_3179 | MW7_1236 | MW7_3179 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Protein involved in adenosine kinase activity and purine base metabolic process. | 0.775 |
MW7_1236 | apt | MW7_1236 | MW7_0372 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.836 |
MW7_1236 | guaA | MW7_1236 | MW7_1925 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.586 |
MW7_1236 | guaB | MW7_1236 | MW7_1923 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Inosine-5 -monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.770 |
MW7_1236 | purA | MW7_1236 | MW7_3470 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.722 |
MW7_1236 | purB | MW7_1236 | MW7_2381 | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | Adenylosuccinate lyase; Protein involved in N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity and purine base metabolic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.542 |
MW7_3179 | MW7_1236 | MW7_3179 | MW7_1236 | Protein involved in adenosine kinase activity and purine base metabolic process. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.775 |
MW7_3179 | MW7_3180 | MW7_3179 | MW7_3180 | Protein involved in adenosine kinase activity and purine base metabolic process. | Outer membrane lipoprotein. | 0.768 |
MW7_3179 | apt | MW7_3179 | MW7_0372 | Protein involved in adenosine kinase activity and purine base metabolic process. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.827 |
MW7_3179 | glk | MW7_3179 | MW7_2802 | Protein involved in adenosine kinase activity and purine base metabolic process. | Glucokinase; Protein involved in glucokinase activity and starch metabolic process; Belongs to the bacterial glucokinase family. | 0.771 |
MW7_3179 | guaA | MW7_3179 | MW7_1925 | Protein involved in adenosine kinase activity and purine base metabolic process. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.812 |
MW7_3179 | guaB | MW7_3179 | MW7_1923 | Protein involved in adenosine kinase activity and purine base metabolic process. | Inosine-5 -monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.760 |
MW7_3179 | hisA | MW7_3179 | MW7_3299 | Protein involved in adenosine kinase activity and purine base metabolic process. | Protein involved in 1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase activity and histidine biosynthetic process. | 0.848 |
MW7_3179 | prs | MW7_3179 | MW7_0348 | Protein involved in adenosine kinase activity and purine base metabolic process. | Phosphoribosylpyrophosphate synthetase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily. | 0.779 |
MW7_3179 | purA | MW7_3179 | MW7_3470 | Protein involved in adenosine kinase activity and purine base metabolic process. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. | 0.820 |
MW7_3179 | purB | MW7_3179 | MW7_2381 | Protein involved in adenosine kinase activity and purine base metabolic process. | Adenylosuccinate lyase; Protein involved in N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity and purine base metabolic process; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.753 |
MW7_3180 | MW7_3179 | MW7_3180 | MW7_3179 | Outer membrane lipoprotein. | Protein involved in adenosine kinase activity and purine base metabolic process. | 0.768 |
apt | MW7_1236 | MW7_0372 | MW7_1236 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Adenosine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism. | 0.836 |
apt | MW7_3179 | MW7_0372 | MW7_3179 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Protein involved in adenosine kinase activity and purine base metabolic process. | 0.827 |
apt | guaA | MW7_0372 | MW7_1925 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.992 |