STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cofC2-phospho-L-lactate guanylyltransferase CofC; Guanylyltransferase that catalyzes the activation of phosphoenolpyruvate (PEP) as enolpyruvoyl-2-diphospho-5'-guanosine, via the condensation of PEP with GTP. It is involved in the biosynthesis of coenzyme F420, a hydride carrier cofactor. (252 aa)    
Predicted Functional Partners:
cofH
FO synthase; Protein involved in transferase activity, transferring alkyl or aryl (other than methyl) groups and coenzyme biosynthetic process.
   
 0.992
MW7_3332
Lppg:fo 2-phospho-l-lactate transferase; Protein involved in magnesium ion binding and cofactor biosynthetic process.
 
  
 0.984
cofE
Oxidoreductase; Protein involved in coenzyme F420-0 gamma-glutamyl ligase activity and cofactor biosynthetic process.
 
   
 0.961
npdG
NADPH-dependent reductase; Protein involved in nucleotide binding and oxidation reduction.
 
     0.935
MW7_3367
Alkanesulfonate monooxygenase; Protein involved in oxidoreductase activity and oxidation reduction.
 
   
 0.803
MW7_3328
Nitroreductase; Protein involved in oxidoreductase activity.
 
   
 0.777
MW7_3329
Carbonic anhydrase; Reversible hydration of carbon dioxide. Belongs to the beta-class carbonic anhydrase family.
       0.709
MW7_3365
Protein involved in CoA-transferase activity and metabolic process.
  
     0.615
pxpA
Hypothetical protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
       0.573
MW7_3366
Protein involved in CoA-transferase activity and metabolic process.
 
     0.531
Your Current Organism:
Burkholderiaceae bacterium PBA
NCBI taxonomy Id: 795666
Other names: B. bacterium PBA
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.