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pcn protein (Halalkalicoccus jeotgali) - STRING interaction network
"pcn" - Proliferating cell nuclear antigen in Halalkalicoccus jeotgali
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
pcnProliferating cell nuclear antigen; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication (247 aa)    
Predicted Functional Partners:
C497_17517
Nucleic acid binding OB-fold tRNA/helicase-type (309 aa)
 
  0.998
C497_13251
Nucleic acid binding OB-fold tRNA/helicase-type (422 aa)
 
  0.997
C497_09953
Replication factor A (482 aa)
 
  0.997
priS
DNA primase, small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] (393 aa)
 
 
  0.997
rfcL
Replication factor C large subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (482 aa)
 
  0.996
fen
Flap endonuclease-1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (325 aa)
 
  0.996
C497_07354
DNA-directed DNA polymerase type II (894 aa)
 
  0.995
C497_06032
Ribonucleotide reductase subunit beta-like protein (297 aa)
     
 
  0.994
C497_18517
Ribonucleotide-diphosphate reductase subunit beta (330 aa)
     
 
  0.994
rfc
Replication factor C small subunit; Part of the RFC clamp loader complex which loads the PCNA sliding clamp onto DNA (329 aa)
 
  0.994
Your Current Organism:
Halalkalicoccus jeotgali
NCBI taxonomy Id: 795797
Other names: H. jeotgali, H. jeotgali B3, Halalkalicoccus, Halalkalicoccus Xue et al. 2005, Halalkalicoccus jeotgali, Halalkalicoccus jeotgali B3, Halalkalicoccus jeotgali DSM 18796, Halalkalicoccus jeotgali JCM 14584, Halalkalicoccus jeotgali Roh et al. 2007, Halalkalicoccus jeotgali str. B3, Halalkalicoccus jeotgali strain B3
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