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pan protein (Halalkalicoccus jeotgali) - STRING interaction network
"pan" - Proteasome-activating nucleotidase in Halalkalicoccus jeotgali
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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panProteasome-activating nucleotidase; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C- terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C-termini of the proteasomal ATPase function like a ’key in a lock’ to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase- [...] (403 aa)    
Predicted Functional Partners:
psmA
Proteasome subunit alpha; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (255 aa)
   
  0.994
psmB
Proteasome subunit beta; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation (247 aa)
   
  0.993
rad50
Chromosome segregation protein; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. Rad50 controls the balance between DNA end bridging and DNA resection via ATP-dependent structural rearrangements of the Rad50/Mre11 complex (890 aa)
   
 
  0.992
C497_10423
20S proteasome subunits A and B (179 aa)
     
  0.986
C497_10068
Hypothetical protein (150 aa)
     
  0.984
C497_11872
Proteasome Rpn11 subunit JAMM motif protein (170 aa)
     
  0.984
C497_12082
Hypothetical protein (136 aa)
     
  0.984
HacjB3_04005
AAA ATPase central domain-containing protein (445 aa)
   
0.955
C497_03142
Hypothetical protein (723 aa)
   
0.949
C497_02857
AAA family ATPase (741 aa)
   
0.948
Your Current Organism:
Halalkalicoccus jeotgali
NCBI taxonomy Id: 795797
Other names: H. jeotgali, H. jeotgali B3, Halalkalicoccus, Halalkalicoccus Xue et al. 2005, Halalkalicoccus jeotgali, Halalkalicoccus jeotgali B3, Halalkalicoccus jeotgali DSM 18796, Halalkalicoccus jeotgali JCM 14584, Halalkalicoccus jeotgali Roh et al. 2007, Halalkalicoccus jeotgali str. B3, Halalkalicoccus jeotgali strain B3
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