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grpE protein (Halalkalicoccus jeotgali) - STRING interaction network
"grpE" - GrpE protein in Halalkalicoccus jeotgali
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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grpEGrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP- dependent [...] (198 aa)    
Predicted Functional Partners:
dnaK
Molecular chaperone DnaK; Acts as a chaperone (637 aa)
 
  0.999
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (380 aa)
 
 
  0.994
C497_14682
Hypothetical protein (158 aa)
 
 
  0.983
C497_15583
Thermosome (562 aa)
   
  0.954
C497_09483
Thermosome subunit alpha (519 aa)
   
  0.954
HacjB3_00205
Thermosome (550 aa)
   
  0.954
C497_07804
DnaJ N-terminal domain-containing protein (220 aa)
   
  0.926
C497_02897
Chaperone protein dnaJ (147 aa)
 
  0.860
C497_15057
Prenyltransferase (315 aa)
   
 
    0.729
C497_11463
Prenyltransferase; Prenyltransferase that catalyzes the transfer of the geranylgeranyl moiety of geranylgeranyl diphosphate (GGPP) to the C2 hydroxyl of (S)-3-O-geranylgeranylglyceryl phosphate (GGGP). This reaction is the second ether-bond-formation step in the biosynthesis of archaeal membrane lipids (277 aa)
     
 
    0.691
Your Current Organism:
Halalkalicoccus jeotgali
NCBI taxonomy Id: 795797
Other names: H. jeotgali, H. jeotgali B3, Halalkalicoccus, Halalkalicoccus Xue et al. 2005, Halalkalicoccus jeotgali, Halalkalicoccus jeotgali B3, Halalkalicoccus jeotgali DSM 18796, Halalkalicoccus jeotgali JCM 14584, Halalkalicoccus jeotgali Roh et al. 2007, Halalkalicoccus jeotgali str. B3, Halalkalicoccus jeotgali strain B3
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