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C497_08839 protein (Halalkalicoccus jeotgali) - STRING interaction network
"C497_08839" - DNA-(apurinic or apyrimidinic site) lyase in Halalkalicoccus jeotgali
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
C497_08839DNA-(apurinic or apyrimidinic site) lyase (267 aa)    
Predicted Functional Partners:
C497_18542
Hef nuclease (799 aa)
     
 
  0.881
nth
Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N- glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3’ to the AP site by a beta-elimination, leaving a 3’-terminal unsaturated sugar and a product with a terminal 5’-phosphate (227 aa)
   
   
 
0.831
HacjB3_12550
PHP domain-containing protein (580 aa)
 
 
  0.819
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation (692 aa)
   
   
  0.809
C497_08834
Hypothetical protein (140 aa)
 
          0.784
C497_08829
Lipoate-protein ligase (277 aa)
 
        0.769
fen
Flap endonuclease-1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. Binds the unpaired 3’-DNA end and kinks the DNA to facilitate 5’ cleavage specificity. Cleaves one nucleotide into the double- stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] (325 aa)
   
 
  0.758
C497_08988
Bifunctional purine biosynthesis protein PurH (525 aa)
         
  0.756
nfo
DNA-(apurinic or apyrimidinic site) lyase; Endonuclease IV plays a role in DNA repair. It cleaves phosphodiester bonds at apurinic or apyrimidinic sites (AP sites) to produce new 5’-ends that are base-free deoxyribose 5-phosphate residues. It preferentially attacks modified AP sites created by bleomycin and neocarzinostatin (276 aa)
   
 
  0.694
tgtA
7-cyano-7-deazaguanine tRNA-ribosyltransferase; Exchanges the guanine residue with 7-cyano-7- deazaguanine (preQ0) at position 15 in the dihydrouridine loop (D- loop) of archaeal tRNAs (485 aa)
 
     
  0.670
Your Current Organism:
Halalkalicoccus jeotgali
NCBI taxonomy Id: 795797
Other names: H. jeotgali, H. jeotgali B3, Halalkalicoccus, Halalkalicoccus Xue et al. 2005, Halalkalicoccus jeotgali, Halalkalicoccus jeotgali B3, Halalkalicoccus jeotgali DSM 18796, Halalkalicoccus jeotgali JCM 14584, Halalkalicoccus jeotgali Roh et al. 2007, Halalkalicoccus jeotgali str. B3, Halalkalicoccus jeotgali strain B3
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