STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PRKACA-2cAMP-dependent protein kinase catalytic subunit alpha; Belongs to the protein kinase superfamily. (345 aa)    
Predicted Functional Partners:
PRKAR2A
cAMP-dependent protein kinase type II-alpha regulatory subunit.
 
 
 0.974
PRKAA2
Non-specific serine/threonine protein kinase.
  
0.946
Psn
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
     
 0.937
Gabarapl2
Gamma-aminobutyric acid receptor-associated protein-like 2.
   
 
 0.931
CSKR_3572s
Catenin beta.
     
 0.926
unc-51
Serine/threonine-protein kinase unc-51.
    
 
0.925
Atg13
Autophagy-related protein 13-like protein.
     
 0.915
Pkg21D
cGMP-dependent protein kinase.
 
 
 0.913
ROCK1
Rho-associated protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
  
 
0.906
PRKACB
cAMP-dependent protein kinase catalytic subunit beta.
  
  
0.903
Your Current Organism:
Clonorchis sinensis
NCBI taxonomy Id: 79923
Other names: C. sinensis, oriental liver fluke
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.