STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rad17RAD17 checkpoint clamp loader component. (685 aa)    
Predicted Functional Partners:
rfc5
Replication factor C (activator 1) 5.
   
 0.999
rfc3
Replication factor C (activator 1) 3.
   
 0.999
Rfc2
Replication factor C (activator 1) 2.
    
 0.999
Rfc4
Replication factor C (activator 1) 4.
   
 0.999
wrn
WRN RecQ like helicase.
   
 0.990
hus1
Checkpoint protein; Belongs to the HUS1 family.
   
 0.989
rad1
RAD1 homolog (S. pombe).
   
 0.986
ENSAMXP00000027946
SMC5-SMC6 complex localization factor 1.
  
 0.978
W5KFB1_ASTMX
RAD9 checkpoint clamp component B.
   
 0.975
rad9a
Cell cycle checkpoint control protein; Belongs to the rad9 family.
   
 0.975
Your Current Organism:
Astyanax mexicanus
NCBI taxonomy Id: 7994
Other names: A. mexicanus, Mexican tetra, blind cave fish
Server load: low (36%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.