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The next version of STRING is ready for use in your analyses: updated networks across STRING newly available directed regulatory networks a new typed view showing functional, physical, and regulatory edges in one network new clustering options and cluster-based layouts … and much more!
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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC105015783Uncharacterized protein. (1019 aa)    
Predicted Functional Partners:
ksr2
Kinase suppressor of ras 2.
    
 0.563
ksr1
Kinase suppressor of ras 1a.
    
 0.563
LOC105012233
Kinase suppressor of ras 1b.
    
 0.563
raf1
Raf-1 proto-oncogene, serine/threonine kinase b.
    
 0.531
LOC105029139
Raf-1 proto-oncogene, serine/threonine kinase a.
    
 0.531
araf
A-Raf proto-oncogene, serine/threonine kinase.
    
 0.531
braf
B-Raf proto-oncogene, serine/threonine kinase.
    
 0.531
SAMD12
Sterile alpha motif domain containing 12.
    
 0.491
rasl11b
RAS-like, family 11, member B.
    
 0.443
ralb
Uncharacterized protein.
    
 0.439
Your Current Organism:
Esox lucius
NCBI taxonomy Id: 8010
Other names: E. lucius, northern pike
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