STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IMPDHInosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. (502 aa)    
Predicted Functional Partners:
A0A060ZJU2
Uncharacterized protein.
 
 0.953
A0A060YMY2
Uncharacterized protein.
 
 0.951
A0A060YRF2
Glutamine amidotransferase type-1 domain-containing protein.
 
 0.947
A0A060YRQ6
GMP_synt_C domain-containing protein.
  
 0.936
A0A060ZAW9
GMP_synt_C domain-containing protein.
  
 0.936
A0A060Y3Y0
Uncharacterized protein.
  
 0.927
A0A060Z304
Uncharacterized protein.
  
 
 0.917
A0A060Z385
Uncharacterized protein.
  
 
 0.917
A0A060YK16
Uncharacterized protein.
   
 0.903
A0A060ZF19
Uncharacterized protein.
   
 0.903
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
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