STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BMT2-2S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (394 aa)    
Predicted Functional Partners:
A0A060XXJ7
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
   
 0.972
A0A060WIJ2
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.932
A0A060X1P8
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.932
A0A060X2M1
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.932
A0A060Y189
Uncharacterized protein.
    
 0.932
A0A060Y2C4
STPPase_N domain-containing protein.
    
 0.932
A0A060VY18
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.925
A0A060X3J8
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.925
A0A060XRX7
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.925
A0A060YTQ2
Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family.
    
 0.925
Your Current Organism:
Oncorhynchus mykiss
NCBI taxonomy Id: 8022
Other names: O. mykiss, Oncorhynchus nerka mykiss, Parasalmo mykiss, Salmo mykiss, rainbow trout
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.