STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fbxl4F-box and leucine-rich repeat protein 4. (613 aa)    
Predicted Functional Partners:
skp1
S-phase kinase-associated protein 1; Belongs to the SKP1 family.
   
 0.868
cul1
Cullin 1b; Belongs to the cullin family.
    
 0.819
rbx1
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.730
commd4
COMM domain containing 4.
   
 0.703
LOC103471028
COMM domain containing 5.
     
 0.688
LOC103479391
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.676
LOC103474461
Cullin 3; Belongs to the cullin family.
    
 0.676
LOC103475981
Ubiquitin-like domain-containing protein.
    
 0.673
LOC103478889
NEDD8 ubiquitin like modifier.
    
 0.673
eloc
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.658
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.