STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tpp2Tripeptidyl peptidase 2. (1279 aa)    
Predicted Functional Partners:
atg5
Autophagy protein 5; Involved in autophagic vesicle formation.
      
 0.605
blmh
Bleomycin hydrolase; Belongs to the peptidase C1 family.
   
 
 0.574
mipep
Mitochondrial intermediate peptidase.
   
  
 0.554
ctsa
Carboxypeptidase; Belongs to the peptidase S10 family.
   
 
 0.539
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.500
rxfp1
Relaxin family peptide receptor 1.
   
 0.500
rxfp2
Relaxin family peptide receptor 2a.
   
 0.500
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
   
 0.500
polb
DNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity.
   
   0.475
LOC103460439
V-type proton ATPase subunit G; Catalytic subunit of the peripheral V1 complex of vacuolar ATPase (V-ATPase). V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.
      
 0.471
Your Current Organism:
Poecilia reticulata
NCBI taxonomy Id: 8081
Other names: Acanthophacelus reticulata, P. reticulata, Poecilia (Acanthophacelus) reticulata, Poecilia latipinna reticulata, guppy
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.