STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
smad7Mothers against decapentaplegic homolog. (378 aa)    
Predicted Functional Partners:
SMURF2
E3 ubiquitin-protein ligase.
    
 0.999
smurf1
E3 ubiquitin-protein ligase.
    
 0.981
smad9
Mothers against decapentaplegic homolog.
   
0.947
LOC102227900
Mothers against decapentaplegic homolog.
   
0.947
smad3
Mothers against decapentaplegic homolog.
   
0.936
LOC102224322
Mothers against decapentaplegic homolog.
   
0.936
SMAD3
Mothers against decapentaplegic homolog.
   
0.936
smad6
Mothers against decapentaplegic homolog.
  
  
0.907
LOC102223630
Mothers against decapentaplegic homolog.
     
0.906
LOC102234136
SMAD specific E3 ubiquitin protein ligase 2.
    
 0.825
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.