STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcsk1Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (772 aa)    
Predicted Functional Partners:
LOC102229500
Uncharacterized protein.
     
 0.756
POMC
Proopiomelanocortin.
     
 0.756
bsnd
Uncharacterized protein.
      
 0.650
Usp24
Ubiquitin specific peptidase 24.
      
 0.649
LOC102229304
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.643
ins
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
   
 
 0.643
rxfp1
Relaxin family peptide receptor 1.
   
 0.571
lgr4
Leucine-rich repeat containing G protein-coupled receptor 4.
   
 0.571
rxfp2
Relaxin family peptide receptor 2a.
   
 0.571
LGR5
Leucine rich repeat containing G protein-coupled receptor 5.
   
 0.571
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
Server load: low (28%) [HD]