STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gpn2GPN-loop GTPase 2; Small GTPase required for proper localization of RNA polymerase II and III (RNAPII and RNAPIII). May act at an RNAP assembly step prior to nuclear import; Belongs to the GPN-loop GTPase family. (313 aa)    
Predicted Functional Partners:
gpn1
GPN-loop GTPase; Small GTPase required for proper nuclear import of RNA polymerase II (RNAPII). May act at an RNAP assembly step prior to nuclear import.
    
 
0.952
polr2b
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 
 0.897
rpap1
RNA polymerase II associated protein 1.
    
 
 0.870
polr2c
Polymerase (RNA) II (DNA directed) polypeptide C.
   
 
 0.862
polr2j
Polymerase (RNA) II (DNA directed) polypeptide J.
    
 
 0.827
polr2l
Polymerase (RNA) II (DNA directed) polypeptide L.
    
 
 0.804
ENSXMAP00000020627
SH3 domain-containing protein.
    
 0.803
ENSXMAP00000022108
Uncharacterized protein.
    
 0.803
ENSXMAP00000024852
EH domain-containing protein.
    
 0.803
LOC102223116
Intersectin 2a.
    
 0.803
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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