STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ESRRBEstrogen-related receptor beta. (477 aa)    
Predicted Functional Partners:
ppargc1a
Peroxisome proliferator-activated receptor gamma, coactivator 1 alpha.
   
 0.836
nrip1
Nuclear receptor interacting protein 1b.
    
 0.660
LOC102229141
POU domain protein.
   
 0.651
ncor1
Nuclear receptor corepressor 1.
    
 0.626
ncor2
Nuclear receptor corepressor 2.
    
 0.626
LOC102226844
Peroxisome proliferator-activated receptor gamma, coactivator 1 beta.
    
 0.585
klf4
Kruppel-like factor 4.
    
 0.580
LOC102237096
Estrogen-related receptor alpha.
  
 
 
0.541
med1
Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
  0.529
NR0B1
Nuclear receptor subfamily 0 group B member 1.
    
 
0.519
Your Current Organism:
Xiphophorus maculatus
NCBI taxonomy Id: 8083
Other names: Platypoecilus maculatus, X. maculatus, southern platyfish
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.