STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hrasHRas proto-oncogene, GTPase a. (189 aa)    
Predicted Functional Partners:
braf
B-Raf proto-oncogene, serine/threonine kinase.
   
 0.985
rasa1
RAS p21 protein activator (GTPase activating protein) 1a.
   
 0.980
raf1
Raf-1 proto-oncogene, serine/threonine kinase a.
   
 0.976
araf
A-Raf proto-oncogene, serine/threonine kinase.
   
 0.976
Nf1
Uncharacterized protein.
   
 0.974
sos2
Son of sevenless homolog 2 (Drosophila).
   
 0.966
rassf5
Ras association domain family member 5.
    
 0.959
rapgef2
Rap guanine nucleotide exchange factor (GEF) 2.
   
 0.955
PIK3CA
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.954
LOC101168152
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
 0.954
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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