STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
insInsulin A chain; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (113 aa)    
Predicted Functional Partners:
LOC100707581
Tyrosine-protein kinase receptor.
    
 0.976
LOC100711993
Tyrosine-protein kinase receptor.
    
 0.976
LOC100704156
Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
  
  
 
0.902
LOC100692389
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
    
 0.882
LOC100534576
Preproghrelin.
     
 0.868
LOC100704325
Insulin receptor substrate 2a.
     
 0.852
irs2
Insulin receptor substrate 2b.
     
 0.818
I3JB37_ORENI
Si:ch73-335l21.1.
     
 0.818
LOC100709921
Insulin receptor substrate 4a.
     
 0.818
I3J8S9_ORENI
Si:ch211-284e13.4.
     
 0.818
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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