STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kiss2Kisspeptin-2. (124 aa)    
Predicted Functional Partners:
gnrh3
Gonadotropin-releasing hormone.
      
 0.866
gnrh2
Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family.
      
 0.740
GOLT1B
Golgi transport 1Ba.
      
 0.668
LOC100534501
Luteinizing hormone, beta polypeptide.
      
 0.665
gpr54
G-protein coupled receptor 54; Receptor speculated to be essential for sexual development. May regulate gonadotropin-releasing hormone (GnRH) secretion. The receptor expression could be a 'stop signal' for GnRH1, GnRH2, and GnRH3 neuronal migration, leading to suppression of cell growth and modulation of GnRH secretion, which is important for normal sexual development.
      
 0.652
gnrh1
Uncharacterized protein.
      
 0.601
fshb
FSH beta subunit.
      
 0.592
I3JA86_ORENI
Uncharacterized protein.
      
 0.587
gys2
Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.
      
 0.525
LOC102082036
Tachykinin-3-like precursor.
      
 0.495
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.