STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prdx5Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily. (190 aa)    
Predicted Functional Partners:
txn2
Thioredoxin 2.
   
 0.951
prdx3
Peroxiredoxin 3.
   
 0.948
LOC100690837
Thioredoxin; Belongs to the thioredoxin family.
   
 0.944
LOC100692536
Thioredoxin; Belongs to the thioredoxin family.
   
 0.944
LOC100692805
Thioredoxin; Belongs to the thioredoxin family.
   
 0.944
I3JR68_ORENI
NME/NM23 family member 8; Belongs to the NDK family.
   
 0.938
LOC100703194
Peroxiredoxin 1.
   
 0.933
gsr
Glutathione reductase; Maintains high levels of reduced glutathione in the cytosol. Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.
    
 0.898
LOC100709606
Peroxiredoxin 4.
   
 0.887
LOC100702211
Peroxiredoxin 2.
   
 0.882
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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