| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| LOC100691054 | TRMT5 | ENSONIP00000007393 | ENSONIP00000025340 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | 0.732 |
| LOC100691054 | lcmt1 | ENSONIP00000007393 | ENSONIP00000024900 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. | 0.555 |
| LOC100691054 | lcmt2 | ENSONIP00000007393 | ENSONIP00000017345 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | Leucine carboxyl methyltransferase 2. | 0.704 |
| LOC100691054 | trmt12 | ENSONIP00000007393 | ENSONIP00000003274 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA methyltransferase 12 homolog. | 0.788 |
| LOC100691054 | tyw3 | ENSONIP00000007393 | ENSONIP00000049874 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | 0.788 |
| LOC100691054 | tyw5 | ENSONIP00000007393 | ENSONIP00000021140 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA-yW synthesizing protein 5. | 0.630 |
| LOC100691054 | wdr4 | ENSONIP00000007393 | ENSONIP00000080524 | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.595 |
| TRMT5 | LOC100691054 | ENSONIP00000025340 | ENSONIP00000007393 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 1 homolog (S. cerevisiae). | 0.732 |
| TRMT5 | lcmt1 | ENSONIP00000025340 | ENSONIP00000024900 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Leucine carboxyl methyltransferase 1; Methylates the carboxyl group of the C-terminal leucine residue of protein phosphatase 2A catalytic subunits to form alpha- leucine ester residues; Belongs to the methyltransferase superfamily. LCMT family. | 0.492 |
| TRMT5 | lcmt2 | ENSONIP00000025340 | ENSONIP00000017345 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Leucine carboxyl methyltransferase 2. | 0.696 |
| TRMT5 | trmt112 | ENSONIP00000025340 | ENSONIP00000006769 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA methyltransferase subunit 11-2. | 0.852 |
| TRMT5 | trmt12 | ENSONIP00000025340 | ENSONIP00000003274 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA methyltransferase 12 homolog. | 0.690 |
| TRMT5 | tsr3 | ENSONIP00000025340 | ENSONIP00000025147 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | Probable ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis. | 0.505 |
| TRMT5 | tyw3 | ENSONIP00000025340 | ENSONIP00000049874 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 3 homolog (S. cerevisiae). | 0.769 |
| TRMT5 | tyw5 | ENSONIP00000025340 | ENSONIP00000021140 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA-yW synthesizing protein 5. | 0.519 |
| TRMT5 | wdr4 | ENSONIP00000025340 | ENSONIP00000080524 | tRNA (guanine(37)-N1)-methyltransferase; Specifically methylates the N1 position of guanosine-37 in various cytoplasmic and mitochondrial tRNAs. Methylation is not dependent on the nature of the nucleoside 5' of the target nucleoside. This is the first step in the biosynthesis of wybutosine (yW), a modified base adjacent to the anticodon of tRNAs and required for accurate decoding; Belongs to the TRM5 / TYW2 family. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.620 |
| bud23 | trmt112 | ENSONIP00000004784 | ENSONIP00000006769 | BUD23 rRNA methyltransferase and ribosome maturation factor. | tRNA methyltransferase subunit 11-2. | 0.998 |
| bud23 | trmt12 | ENSONIP00000004784 | ENSONIP00000003274 | BUD23 rRNA methyltransferase and ribosome maturation factor. | tRNA methyltransferase 12 homolog. | 0.594 |
| bud23 | tsr3 | ENSONIP00000004784 | ENSONIP00000025147 | BUD23 rRNA methyltransferase and ribosome maturation factor. | Probable ribosome biogenesis protein; Probable pre-rRNA processing protein involved in ribosome biogenesis. | 0.735 |
| bud23 | wdr4 | ENSONIP00000004784 | ENSONIP00000080524 | BUD23 rRNA methyltransferase and ribosome maturation factor. | tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family. | 0.745 |