STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PtproProtein tyrosine phosphatase receptor type O. (1214 aa)    
Predicted Functional Partners:
LOC100701740
Macrophage stimulating 1 receptor a.
    
 0.715
mst1r
Macrophage stimulating 1 receptor b.
    
 0.715
met
MET proto-oncogene, receptor tyrosine kinase.
    
 0.715
rpl13a
Ribosomal protein L13a; Belongs to the universal ribosomal protein uL13 family.
   
  0.521
ENSONIP00000036848
Receptor-type tyrosine-protein kinase FLT3.
   
 0.477
pdgfra
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
   
 0.477
I3IU13_ORENI
Pleiotrophin.
   
 0.450
LOC100690943
Tyrosine-protein kinase receptor.
    
 0.442
alk
Tyrosine-protein kinase receptor.
    
 0.442
il1rap
Uncharacterized protein.
  
 0.420
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.