STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
brip1BRCA1 interacting protein C-terminal helicase 1. (1213 aa)    
Predicted Functional Partners:
topbp1
DNA topoisomerase II binding protein 1.
   
 0.991
brca1
Uncharacterized protein.
   
 0.989
Mlh1
MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli).
   
 0.981
palb2
PALB2_WD40 domain-containing protein.
   
 0.962
pms2
PMS1 homolog 2, mismatch repair system component.
   
 0.959
slf1
BRCT domain-containing protein.
   
 0.916
ercc3
Excision repair cross-complementation group 3.
   
 0.911
LOC100696048
General transcription factor IIH subunit.
    
 0.909
gtf2h4
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
    
 0.907
gtf2h1
General transcription factor IIH, polypeptide 1.
    
 0.906
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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