STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rnf40E3 ubiquitin protein ligase. (1005 aa)    
Predicted Functional Partners:
leo1
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.977
ube2b
Ubiquitin-conjugating enzyme E2B (RAD6 homolog); Belongs to the ubiquitin-conjugating enzyme family.
    
 0.873
LOC100710794
Ubiquitin-conjugating enzyme E2 A.
    
 0.873
ube2a
Ubiquitin conjugating enzyme E2 A, like; Belongs to the ubiquitin-conjugating enzyme family.
    
 0.873
cdc73
Ro60, Y RNA binding protein.
   
 0.851
paf1
PAF1 homolog, Paf1/RNA polymerase II complex component.
    
 0.839
ENSONIP00000038802
Uncharacterized protein LOC100692229 isoform X1.
    
 0.813
setd2
SET domain containing 2, histone lysine methyltransferase.
   
 
 0.803
ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.793
LOC100696120
WW domain-containing protein.
   
 0.775
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.