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aaxA protein (Chlamydia trachomatis) - STRING interaction network
"aaxA" - Porin in Chlamydia trachomatis
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
aaxAPorin; Facilitates L-arginine uptake, as part of the AaxABC system. The arginine uptake by the bacterium in the macrophage may be a virulence factor against the host innate immune response (466 aa)    
Predicted Functional Partners:
aaxB
annotation not available (195 aa)
         
  0.815
aaxC
annotation not available (483 aa)
         
  0.787
aroD
3-dehydroquinate dehydratase; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis-dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3- dehydroshikimate; Belongs to the type-I 3-dehydroquinase family (478 aa)
   
        0.668
ompB
annotation not available (340 aa)
           
  0.660
O172_02030
annotation not available (261 aa)
              0.632
ompA
Major outer membrane porin, serovar F; In elementary bodies (EBs, the infectious stage, which is able to survive outside the host cell) provides the structural integrity of the outer envelope through disulfide cross-links with the small cysteine-rich protein and the large cysteine-rich periplasmic protein. It has been described in publications as the Sarkosyl-insoluble COMC (Chlamydia outer membrane complex), and serves as the functional equivalent of peptidoglycan (By similarity) (395 aa)
           
  0.594
aroB
3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino- heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ) (373 aa)
              0.553
aroC
Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system (357 aa)
              0.553
aroK
Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family (184 aa)
              0.553
aroA_1
annotation not available (440 aa)
              0.553
Your Current Organism:
Chlamydia trachomatis
NCBI taxonomy Id: 813
Other names: ATCC VR-571B, C. trachomatis, Chlamydia trachomatis, Chlamydozoon trachomatis, DSM 19440, Rickettsia trachomae, Rickettsia trachomatis, strain A/Har-13
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