node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PPE35 | Rv0034 | Rv1918c | Rv0034 | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | 0.438 |
PPE35 | acpA | Rv1918c | Rv0033 | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | 0.604 |
PPE35 | bioF2 | Rv1918c | Rv0032 | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | Putative 8-amino-7-oxononanoate synthase 2; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.761 |
PPE35 | fadD34 | Rv1918c | Rv0035 | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase); Rv0035, (MTCY10H4.35), len: 562 aa. Probable fadD34,fatty-acid-CoA synthetase, similar to many. | 0.744 |
Rv0034 | PPE35 | Rv0034 | Rv1918c | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | 0.438 |
Rv0034 | acpA | Rv0034 | Rv0033 | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | 0.983 |
Rv0034 | bioF2 | Rv0034 | Rv0032 | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | Putative 8-amino-7-oxononanoate synthase 2; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.971 |
Rv0034 | fadD34 | Rv0034 | Rv0035 | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase); Rv0035, (MTCY10H4.35), len: 562 aa. Probable fadD34,fatty-acid-CoA synthetase, similar to many. | 0.982 |
acpA | PPE35 | Rv0033 | Rv1918c | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | Rv1918c, (MTV050.02c), len: 987 aa. PPE35, Member of the Mycobacterium tuberculosis PPE family of glycine-rich proteins. Similar to MTCY28.16|Z95890 Mycobacterium tuberculosis cosmid (1053 aa), FASTA scores: opt: 3404,E(): 0, (65.6% identity in 1058 aa overlap). Also similar to MTV004.05, MTY13E10.17, MTV014.03, MTCY3C7.23,MTCY6G11.05, MTCY48.17, MTV004.03, MTCY31.07, MTCY4C12.36,MTCY180.01, etc. | 0.604 |
acpA | Rv0034 | Rv0033 | Rv0034 | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | Rv0034, (MTCY10H4.34), len: 131 aa. Conserved hypothetical protein, showing weak similarity to AE001980|AE001980_7 hypothetical protein from Deinococcus radiodurans (120 aa), FASTA scores: opt: 141, E(): 0.0028,(29.3% identity in 123 aa overlap). | 0.983 |
acpA | bioF2 | Rv0033 | Rv0032 | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | Putative 8-amino-7-oxononanoate synthase 2; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.973 |
acpA | fadD34 | Rv0033 | Rv0035 | Probable acyl carrier protein AcpA (ACP); Rv0033, (MTCY10H4.33), len: 87 aa. Probable acpA (alternate gene name: acpP), acyl carrier protein, similar to others. Also similar to proteins of Mycobacterium tuberculosis Rv1344 and Rv2244 (31.5% identity in 73 aa overlap). | Probable fatty-acid-CoA ligase FadD34 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase); Rv0035, (MTCY10H4.35), len: 562 aa. Probable fadD34,fatty-acid-CoA synthetase, similar to many. | 0.987 |
bioA | bioB | Rv1568 | Rv1589 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate. | Probable biotin synthetase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | 0.999 |
bioA | bioD | Rv1568 | Rv1570 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate. | Dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. | 0.999 |
bioA | bioF1 | Rv1568 | Rv1569 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate. | 8-amino-7-oxononanoate synthase 1; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. To a lesser extent, can also utilize D-alanine instead of L-alanine as substrate. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. | 0.999 |
bioA | bioF2 | Rv1568 | Rv0032 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate. | Putative 8-amino-7-oxononanoate synthase 2; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.989 |
bioB | bioA | Rv1589 | Rv1568 | Probable biotin synthetase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase BioA; Catalyzes the reversible transfer of the alpha-amino group from S-adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor. Can also use sinefungin as substrate. | 0.999 |
bioB | bioD | Rv1589 | Rv1570 | Probable biotin synthetase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | Dethiobiotin synthetase BioD; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. Belongs to the dethiobiotin synthetase family. | 0.999 |
bioB | bioF1 | Rv1589 | Rv1569 | Probable biotin synthetase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | 8-amino-7-oxononanoate synthase 1; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide (By similarity). Can also use pimeloyl-CoA instead of pimeloyl-ACP as substrate. To a lesser extent, can also utilize D-alanine instead of L-alanine as substrate. Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily. | 0.990 |
bioB | bioF2 | Rv1589 | Rv0032 | Probable biotin synthetase BioB; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism. | Putative 8-amino-7-oxononanoate synthase 2; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.923 |