node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1043c | fabG4 | Rv1043c | Rv0242c | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | 0.471 |
Rv1043c | fadB | Rv1043c | Rv0860 | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv0860, (MTV043.53), len: 720 aa. Probable fadB,fatty oxidation protein, equivalent to NP_302422.1|NC_002677 putative fatty oxidation complex alpha subunit from Mycobacterium leprae (714 aa). Also highly similar to others and various proteins involved in fatty acid metabolism, e.g. T35429 probable fatty oxidation protein from Streptomyces coelicolor (733 aa); NP_250428.1|NC_002516 probable 3-hydroxyacyl-CoA dehydrogenase from Pseudomonas aeruginosa (714 aa); NP_418895.1|NC_002696 fatty oxidation complex alpha subunit from Caulobacter crescentus (709 aa); P40939|ECHA_HUMAN trifunctional [...] | 0.491 |
Rv1043c | fadE2 | Rv1043c | Rv0154c | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv0154c, (MTCI5.28c), len: 403 aa. Probable fadE2,acyl-CoA dehydrogenase, similar to many e.g. C-terminal region of O01590 acyl-CoA dehydrogenase (974 aa), FASTA scores: opt: 1150, E(): 0, (50.0% identity in 402 aa overlap); ACDS_MEGEL|Q06319 acyl-CoA dehydrogenase (short-chain) (383 aa), FASTA score: (35.0% identity in 306 aa overlap). Could belong to the acyl-CoA dehydrogenases family. | 0.489 |
Rv1043c | fadE23 | Rv1043c | Rv3140 | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv3140, (MTCY03A2.18c), len: 401 aa. Probable fadE23, acyl-CoA dehydrogenase (1.3.99.-) (see citation below), equivalent to O32891|MLCB1779.31|FADE23|ML0660 putative acyl-CoA dehydrogenase from Mycobacterium leprae (400 aa), FASTA scores: opt: 2307, E(): 3e-136, (89.5% identity in 401 aa overlap). Also similar to others e.g. Q9HUH1|PA4994 from Pseudomonas aeruginosa (402 aa), FASTA scores: opt: 1558, E(): 1.2e-89, (61.0% identity in 400 aa overlap); O31251 from Acinetobacter sp. ADP1 (401 aa),FASTA scores: opt: 1509, E(): 1.3e-86, (58.2% identity in 402 aa overlap); Q9K6D1|ACDA or BH37 [...] | 0.497 |
Rv1043c | fadE24 | Rv1043c | Rv3139 | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv3139, (MTCY03A2.19c), len: 468 aa. Probable fadE24, acyl-CoA dehydrogenase (1.3.99.-), equivalent to O32890|MLCB1779.30|FADE24|ML0661 putative acyl-CoA dehydrogenase from Mycobacterium leprae (465 aa), FASTA scores: opt: 2587, E(): 4e-153, (83.6% identity in 464 aa overlap). Similar to other e.g. Q9HUH0|PA4995 from Pseudomonas aeruginosa (429 aa), FASTA scores: opt: 1139,E(): 2.8e-63, (45.3% identity in 426 aa overlap); Q9K6D0|MMGC|BH3799 from Bacillus halodurans (379 aa), FASTA scores: opt: 603, E(): 4.7e-30, (30.3% identity in 366 aa overlap); Q9K6D1|ACDA|BH3798 from Bacillus halod [...] | 0.493 |
Rv1043c | fadE8 | Rv1043c | Rv0672 | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv0672, (MTCI376.02c), len: 542 aa. Probable fadE8,acyl-CoA dehydrogenase, highly similar to many e.g. CAC33951.1|AL589708 putative acyl-CoA dehydrogenase from Streptomyces coelicolor (557 aa); P33224|AIDB_ECOLI|B4187 aidb protein (acyl-CoA dehydrogenases family) from Escherichia coli strain K12 (546 aa), FASTA scores: opt: 1369, E(): 0, (44.1% identity in 524 aa overlap); etc. Also similar to several other M. tuberculosis proteins e.g. Rv0154c|MTCI5.28c FASTA score: (26.3% identity in 342 aa overlap); etc. Contains acyl-CoA dehydrogenases signature 2 (PS00073). Belongs to the acyl-CoA [...] | 0.491 |
Rv1043c | htdX | Rv1043c | Rv0241c | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Probable 3-hydroxyacyl-thioester dehydratase HtdX; Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity. Displays a broad chain length specificity, with a predilection for the C8 to C12 substrates. | 0.555 |
Rv1043c | htdY | Rv1043c | Rv3389c | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Probable 3-hydroxyacyl-thioester dehydratase HtdY; Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity. In vitro, can hydrate various enoyl-CoA such as (2E)-hexenoyl-CoA, (2E)-octenoyl-CoA, (2E)-decenoyl-CoA, (2E)- dodecenoyl-CoA and (2E)-hexadecenoyl-CoA. May contribute to the persistence of the tuberculosis infection by inducing COX-2 expression in macrophages through MAPK-NF- kappaB signaling pathway. | 0.548 |
Rv1043c | icd1 | Rv1043c | Rv3339c | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Isocitrate dehydrogenase [NADP]; Rv3339c, (MTV016.39c), len: 409 aa. Probable icd1,isocitrate dehydrogenase NADP-dependent, highly similar to many e.g. Q9A5C8|CC2522 from Caulobacter crescentus (403 aa), FASTA scores: opt: 1972, E(): 4.6e-115, (72.45% identity in 403 aa overlap); AAF73472|ICD from Rhizobium meliloti (404 aa), FASTA scores: opt: 1968, E(): 8.1e-115,(73.2% identity in 403 aa overlap); P50215|IDH_SPHYA from Sphingomonas yanoikuyae (406 aa), FASTA scores: opt: 1964,E(): 1.4e-114, (71.45% identity in 403 aa overlap); etc. Contains PS00470 Isocitrate and isopropylmalate dehy [...] | 0.594 |
fabG4 | Rv1043c | Rv0242c | Rv1043c | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv1043c, (MTCY10G2.06), len: 341 aa. Conserved hypothetical protein similar to AL096872|SC5F7.08 putative lipoate-protein ligase from Streptomyces coelicolor (362 aa), FASTA scores: opt: 206, E(): 1.4e-05, (30.3% identity in 201 aa overlap). Weak similarity to P39668|YYXA_BACSU hypothetical protease from Bacillus subtitis (400 aa),FASTA scores: opt: 159, E(): 0.013, (27.1% identity in 210 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.471 |
fabG4 | fadA2 | Rv0242c | Rv0243 | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv0243, (MTV034.09), len: 440 aa. Probable fadA2,acetyl-CoA acyltransferase (3-acyl-CoA thiolase),equivalent, but shorter 17 aa, to AL022486|MLCB1883_14T44879 acetyltransferase from Mycobacterium leprae (457 aa), FASTA scores: opt: 250 7,E(): 0, (87.6% identity in 435 aa overlap). Also highly similar to many e.g. G83046|PA478 probable acyl-CoA thiolase from Pseudomonas aeruginosa (425 aa); AB77293.1|AL160312 putative ketoacyl CoA thiolase from Streptomyces coelicolor (428 aa); P76503|7449731|YFCY_ECOLI|D65007|B2342 probable 3-ketoacyl-CoA thiolase (acetyl-CoA acyltransferase) (beta-ket [...] | 0.992 |
fabG4 | fadB | Rv0242c | Rv0860 | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv0860, (MTV043.53), len: 720 aa. Probable fadB,fatty oxidation protein, equivalent to NP_302422.1|NC_002677 putative fatty oxidation complex alpha subunit from Mycobacterium leprae (714 aa). Also highly similar to others and various proteins involved in fatty acid metabolism, e.g. T35429 probable fatty oxidation protein from Streptomyces coelicolor (733 aa); NP_250428.1|NC_002516 probable 3-hydroxyacyl-CoA dehydrogenase from Pseudomonas aeruginosa (714 aa); NP_418895.1|NC_002696 fatty oxidation complex alpha subunit from Caulobacter crescentus (709 aa); P40939|ECHA_HUMAN trifunctional [...] | 0.603 |
fabG4 | fadE23 | Rv0242c | Rv3140 | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv3140, (MTCY03A2.18c), len: 401 aa. Probable fadE23, acyl-CoA dehydrogenase (1.3.99.-) (see citation below), equivalent to O32891|MLCB1779.31|FADE23|ML0660 putative acyl-CoA dehydrogenase from Mycobacterium leprae (400 aa), FASTA scores: opt: 2307, E(): 3e-136, (89.5% identity in 401 aa overlap). Also similar to others e.g. Q9HUH1|PA4994 from Pseudomonas aeruginosa (402 aa), FASTA scores: opt: 1558, E(): 1.2e-89, (61.0% identity in 400 aa overlap); O31251 from Acinetobacter sp. ADP1 (401 aa),FASTA scores: opt: 1509, E(): 1.3e-86, (58.2% identity in 402 aa overlap); Q9K6D1|ACDA or BH37 [...] | 0.590 |
fabG4 | fadE24 | Rv0242c | Rv3139 | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv3139, (MTCY03A2.19c), len: 468 aa. Probable fadE24, acyl-CoA dehydrogenase (1.3.99.-), equivalent to O32890|MLCB1779.30|FADE24|ML0661 putative acyl-CoA dehydrogenase from Mycobacterium leprae (465 aa), FASTA scores: opt: 2587, E(): 4e-153, (83.6% identity in 464 aa overlap). Similar to other e.g. Q9HUH0|PA4995 from Pseudomonas aeruginosa (429 aa), FASTA scores: opt: 1139,E(): 2.8e-63, (45.3% identity in 426 aa overlap); Q9K6D0|MMGC|BH3799 from Bacillus halodurans (379 aa), FASTA scores: opt: 603, E(): 4.7e-30, (30.3% identity in 366 aa overlap); Q9K6D1|ACDA|BH3798 from Bacillus halod [...] | 0.584 |
fabG4 | fadE8 | Rv0242c | Rv0672 | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Rv0672, (MTCI376.02c), len: 542 aa. Probable fadE8,acyl-CoA dehydrogenase, highly similar to many e.g. CAC33951.1|AL589708 putative acyl-CoA dehydrogenase from Streptomyces coelicolor (557 aa); P33224|AIDB_ECOLI|B4187 aidb protein (acyl-CoA dehydrogenases family) from Escherichia coli strain K12 (546 aa), FASTA scores: opt: 1369, E(): 0, (44.1% identity in 524 aa overlap); etc. Also similar to several other M. tuberculosis proteins e.g. Rv0154c|MTCI5.28c FASTA score: (26.3% identity in 342 aa overlap); etc. Contains acyl-CoA dehydrogenases signature 2 (PS00073). Belongs to the acyl-CoA [...] | 0.605 |
fabG4 | htdX | Rv0242c | Rv0241c | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Probable 3-hydroxyacyl-thioester dehydratase HtdX; Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity. Displays a broad chain length specificity, with a predilection for the C8 to C12 substrates. | 0.998 |
fabG4 | htdY | Rv0242c | Rv3389c | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | Probable 3-hydroxyacyl-thioester dehydratase HtdY; Shows trans-enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydratase activity. In vitro, can hydrate various enoyl-CoA such as (2E)-hexenoyl-CoA, (2E)-octenoyl-CoA, (2E)-decenoyl-CoA, (2E)- dodecenoyl-CoA and (2E)-hexadecenoyl-CoA. May contribute to the persistence of the tuberculosis infection by inducing COX-2 expression in macrophages through MAPK-NF- kappaB signaling pathway. | 0.951 |
fadA2 | fabG4 | Rv0243 | Rv0242c | Rv0243, (MTV034.09), len: 440 aa. Probable fadA2,acetyl-CoA acyltransferase (3-acyl-CoA thiolase),equivalent, but shorter 17 aa, to AL022486|MLCB1883_14T44879 acetyltransferase from Mycobacterium leprae (457 aa), FASTA scores: opt: 250 7,E(): 0, (87.6% identity in 435 aa overlap). Also highly similar to many e.g. G83046|PA478 probable acyl-CoA thiolase from Pseudomonas aeruginosa (425 aa); AB77293.1|AL160312 putative ketoacyl CoA thiolase from Streptomyces coelicolor (428 aa); P76503|7449731|YFCY_ECOLI|D65007|B2342 probable 3-ketoacyl-CoA thiolase (acetyl-CoA acyltransferase) (beta-ket [...] | Rv0242c, (MTV034.08c), len: 454 aa. Probable fabG4,3-oxoacyl-[acyl-carrier protein] reductase, equivalent to 3063883|CAA18568.1|AL022486|MLCB1883_13|T44878 3-oxoacyl-[acyl-carrier protein] reductase homolog from Mycobacterium leprae (454 aa), FASTA scores: opt: 2486,E(): 0, (84.8% identity in 454 aa overlap). C-terminal part highly similar to many FabG proteins e.g. U39441|VHU3944 1_2 from Vibrio harveyi (244 aa), FASTA scores: opt: 562,E(): 3.4e-28, (40.2% identity in 241 aa overlap); U91631|PAU91631_3 from Pseudomonas aeruginosa (247 aa),FASTA scores: opt: 584, E(): 1.5e-29, (44.4% i [...] | 0.992 |
fadA2 | fadB | Rv0243 | Rv0860 | Rv0243, (MTV034.09), len: 440 aa. Probable fadA2,acetyl-CoA acyltransferase (3-acyl-CoA thiolase),equivalent, but shorter 17 aa, to AL022486|MLCB1883_14T44879 acetyltransferase from Mycobacterium leprae (457 aa), FASTA scores: opt: 250 7,E(): 0, (87.6% identity in 435 aa overlap). Also highly similar to many e.g. G83046|PA478 probable acyl-CoA thiolase from Pseudomonas aeruginosa (425 aa); AB77293.1|AL160312 putative ketoacyl CoA thiolase from Streptomyces coelicolor (428 aa); P76503|7449731|YFCY_ECOLI|D65007|B2342 probable 3-ketoacyl-CoA thiolase (acetyl-CoA acyltransferase) (beta-ket [...] | Rv0860, (MTV043.53), len: 720 aa. Probable fadB,fatty oxidation protein, equivalent to NP_302422.1|NC_002677 putative fatty oxidation complex alpha subunit from Mycobacterium leprae (714 aa). Also highly similar to others and various proteins involved in fatty acid metabolism, e.g. T35429 probable fatty oxidation protein from Streptomyces coelicolor (733 aa); NP_250428.1|NC_002516 probable 3-hydroxyacyl-CoA dehydrogenase from Pseudomonas aeruginosa (714 aa); NP_418895.1|NC_002696 fatty oxidation complex alpha subunit from Caulobacter crescentus (709 aa); P40939|ECHA_HUMAN trifunctional [...] | 0.998 |
fadA2 | fadE2 | Rv0243 | Rv0154c | Rv0243, (MTV034.09), len: 440 aa. Probable fadA2,acetyl-CoA acyltransferase (3-acyl-CoA thiolase),equivalent, but shorter 17 aa, to AL022486|MLCB1883_14T44879 acetyltransferase from Mycobacterium leprae (457 aa), FASTA scores: opt: 250 7,E(): 0, (87.6% identity in 435 aa overlap). Also highly similar to many e.g. G83046|PA478 probable acyl-CoA thiolase from Pseudomonas aeruginosa (425 aa); AB77293.1|AL160312 putative ketoacyl CoA thiolase from Streptomyces coelicolor (428 aa); P76503|7449731|YFCY_ECOLI|D65007|B2342 probable 3-ketoacyl-CoA thiolase (acetyl-CoA acyltransferase) (beta-ket [...] | Rv0154c, (MTCI5.28c), len: 403 aa. Probable fadE2,acyl-CoA dehydrogenase, similar to many e.g. C-terminal region of O01590 acyl-CoA dehydrogenase (974 aa), FASTA scores: opt: 1150, E(): 0, (50.0% identity in 402 aa overlap); ACDS_MEGEL|Q06319 acyl-CoA dehydrogenase (short-chain) (383 aa), FASTA score: (35.0% identity in 306 aa overlap). Could belong to the acyl-CoA dehydrogenases family. | 0.802 |