node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0299 | Rv0424c | Rv0299 | Rv0424c | Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312. | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | 0.652 |
Rv0299 | Rv0461 | Rv0299 | Rv0461 | Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312. | Probable transmembrane protein; Rv0461, (MTV038.05), len: 174 aa (start uncertain). Probable transmembrane protein. Nucleotide position 552085 in the genome sequence has been corrected, A:G resulting in Q20Q. | 0.653 |
Rv0421c | Rv0424c | Rv0421c | Rv0424c | Conserved hypothetical protein; Rv0421c, (MTCY22G10.18c), len: 209 aa. Conserved hypothetical protein, showing similarity with NP_103507.1|14022684|BAB49293.1|AP002998 hypothetical protein from Mesorhizobium loti (214 aa). | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | 0.489 |
Rv0421c | thiC | Rv0421c | Rv0423c | Conserved hypothetical protein; Rv0421c, (MTCY22G10.18c), len: 209 aa. Conserved hypothetical protein, showing similarity with NP_103507.1|14022684|BAB49293.1|AP002998 hypothetical protein from Mesorhizobium loti (214 aa). | Probable thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.848 |
Rv0424c | Rv0299 | Rv0424c | Rv0299 | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312. | 0.652 |
Rv0424c | Rv0421c | Rv0424c | Rv0421c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Conserved hypothetical protein; Rv0421c, (MTCY22G10.18c), len: 209 aa. Conserved hypothetical protein, showing similarity with NP_103507.1|14022684|BAB49293.1|AP002998 hypothetical protein from Mesorhizobium loti (214 aa). | 0.489 |
Rv0424c | Rv0426c | Rv0424c | Rv0426c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Possible transmembrane protein; Rv0426c, (MTCY22G10.23c), len: 147 aa. Possible transmembrane protein; has potential transmembrane domains aa 19-41, and aa 61-83. | 0.764 |
Rv0424c | Rv0461 | Rv0424c | Rv0461 | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Probable transmembrane protein; Rv0461, (MTV038.05), len: 174 aa (start uncertain). Probable transmembrane protein. Nucleotide position 552085 in the genome sequence has been corrected, A:G resulting in Q20Q. | 0.870 |
Rv0424c | Rv0560c | Rv0424c | Rv0560c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Rv0560c, (MTCY25D10.39c), len: 241 aa. Possible benzoquinone methyltransferase (see citation below),similar to other hypothetical proteins and methyltransferases e.g. Q54300 methyltransferase (211 aa),FASTA scores: opt: 203, E(): 4.8e-07, (30.9% identity in 136 aa overlap). Similar to Rv3699, Rv1377c, Rv2675c, etc from Mycobacterium tuberculosis. Rv0560c can be induced by salicylate and para-amino-salicylate (pas). | 0.521 |
Rv0424c | Rv1772 | Rv0424c | Rv1772 | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Hypothetical protein; Rv1772, (MTCY28.38), len: 103 aa. Hypothetical unknown protein. | 0.513 |
Rv0424c | ctpH | Rv0424c | Rv0425c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Rv0425c, (MTCY22G10.22c), len: 1539 aa. Possible ctpH, metal cation-transporting P-type ATPase (transmembrane protein), showing some similarity with CAA17934.1|AL022118|13093871|CAC32203.1|AL583926 putative cation-transporting ATPase from Mycobacterium leprae (1609 aa). Also similar to others ATPases e.g. AE000873_1 cation-transporting P-ATPase from Methanobacterium thermoautotrop (844 aa), FASTA score: (30.5% identity in 827 aa overlap); AB69720.1|AL137166 putative transport ATPase from Streptomyces coelicolor (1472 aa); etc. C-terminal region similar to other ATPases from Mycobacteri [...] | 0.652 |
Rv0424c | moaE1 | Rv0424c | Rv3119 | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Molybdopterin synthase catalytic subunit 1; Converts molybdopterin precursor Z into molybdopterin. This requires the incorporation of two sulfur atoms into precursor Z to generate a dithiolene group. The sulfur is provided by MoaD (By similarity); Belongs to the MoaE family. | 0.651 |
Rv0424c | thiC | Rv0424c | Rv0423c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Probable thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. Belongs to the ThiC family. | 0.518 |
Rv0424c | xthA | Rv0424c | Rv0427c | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI); Rv0427c, (MTCY22G10.24c), len: 291 aa. Probable xthA (alternate gene name: xth), exodeoxyribonuclease III protein (see citation below), similar to others e.g. EX3_ECOLI|P09030 exodeoxyribonuclease III from Escherichia Coli strain K12 (268 aa), FASTA scores: opt: 360, E(): 1.2e-17, (29.3% identity in 270 aa overlap); etc. Belongs to the AP/EXOA family of DNA repair enzymes. | 0.496 |
Rv0426c | Rv0424c | Rv0426c | Rv0424c | Possible transmembrane protein; Rv0426c, (MTCY22G10.23c), len: 147 aa. Possible transmembrane protein; has potential transmembrane domains aa 19-41, and aa 61-83. | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | 0.764 |
Rv0426c | ctpH | Rv0426c | Rv0425c | Possible transmembrane protein; Rv0426c, (MTCY22G10.23c), len: 147 aa. Possible transmembrane protein; has potential transmembrane domains aa 19-41, and aa 61-83. | Rv0425c, (MTCY22G10.22c), len: 1539 aa. Possible ctpH, metal cation-transporting P-type ATPase (transmembrane protein), showing some similarity with CAA17934.1|AL022118|13093871|CAC32203.1|AL583926 putative cation-transporting ATPase from Mycobacterium leprae (1609 aa). Also similar to others ATPases e.g. AE000873_1 cation-transporting P-ATPase from Methanobacterium thermoautotrop (844 aa), FASTA score: (30.5% identity in 827 aa overlap); AB69720.1|AL137166 putative transport ATPase from Streptomyces coelicolor (1472 aa); etc. C-terminal region similar to other ATPases from Mycobacteri [...] | 0.666 |
Rv0426c | xthA | Rv0426c | Rv0427c | Possible transmembrane protein; Rv0426c, (MTCY22G10.23c), len: 147 aa. Possible transmembrane protein; has potential transmembrane domains aa 19-41, and aa 61-83. | Probable exodeoxyribonuclease III protein XthA (exonuclease III) (EXO III) (AP endonuclease VI); Rv0427c, (MTCY22G10.24c), len: 291 aa. Probable xthA (alternate gene name: xth), exodeoxyribonuclease III protein (see citation below), similar to others e.g. EX3_ECOLI|P09030 exodeoxyribonuclease III from Escherichia Coli strain K12 (268 aa), FASTA scores: opt: 360, E(): 1.2e-17, (29.3% identity in 270 aa overlap); etc. Belongs to the AP/EXOA family of DNA repair enzymes. | 0.514 |
Rv0461 | Rv0299 | Rv0461 | Rv0299 | Probable transmembrane protein; Rv0461, (MTV038.05), len: 174 aa (start uncertain). Probable transmembrane protein. Nucleotide position 552085 in the genome sequence has been corrected, A:G resulting in Q20Q. | Hypothetical protein; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin Rv0298/MT0312. | 0.653 |
Rv0461 | Rv0424c | Rv0461 | Rv0424c | Probable transmembrane protein; Rv0461, (MTV038.05), len: 174 aa (start uncertain). Probable transmembrane protein. Nucleotide position 552085 in the genome sequence has been corrected, A:G resulting in Q20Q. | Hypothetical protein; Rv0424c, (MTCY22G10.21c), len: 91 aa. Hypothetical unknown protein. | 0.870 |
Rv0461 | Rv0560c | Rv0461 | Rv0560c | Probable transmembrane protein; Rv0461, (MTV038.05), len: 174 aa (start uncertain). Probable transmembrane protein. Nucleotide position 552085 in the genome sequence has been corrected, A:G resulting in Q20Q. | Rv0560c, (MTCY25D10.39c), len: 241 aa. Possible benzoquinone methyltransferase (see citation below),similar to other hypothetical proteins and methyltransferases e.g. Q54300 methyltransferase (211 aa),FASTA scores: opt: 203, E(): 4.8e-07, (30.9% identity in 136 aa overlap). Similar to Rv3699, Rv1377c, Rv2675c, etc from Mycobacterium tuberculosis. Rv0560c can be induced by salicylate and para-amino-salicylate (pas). | 0.520 |