node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0738 | Rv0802c | Rv0738 | Rv0802c | Conserved protein; Rv0738, (MTV041.12), len: 182 aa. Conserved protein,showing weak similarity with hypothetical proteins from Mycobacterium tuberculosis: Rv1727|MTCY04C12.12 (189 aa); MTY13D12_7|Z80343 hypothetical protein from Mycobacterium tuberculosis (194 aa), FASTA scores: opt: 172, E(): 0.0004,(24.2% identity in 178 aa overlap); and C-terminus of Rv0576. | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.546 |
Rv0802c | Rv0738 | Rv0802c | Rv0738 | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Conserved protein; Rv0738, (MTV041.12), len: 182 aa. Conserved protein,showing weak similarity with hypothetical proteins from Mycobacterium tuberculosis: Rv1727|MTCY04C12.12 (189 aa); MTY13D12_7|Z80343 hypothetical protein from Mycobacterium tuberculosis (194 aa), FASTA scores: opt: 172, E(): 0.0004,(24.2% identity in 178 aa overlap); and C-terminus of Rv0576. | 0.546 |
Rv0802c | Rv0804 | Rv0802c | Rv0804 | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Rv0804, (MTCY07H7A.05c), len: 209 aa. Conserved hypothetical protein, showing similarity with C-terminus of Rv1863c|MTCY359.10 conserved hypothetical protein from Mycobacterium tuberculosis (256 aa), FASTA scores: opt: 199, E(): 1.2e-05, (33.2% identity in 220 aa overlap); and Rv0658c. Contains PS01151 Fimbrial biogenesis outer membrane usher protein signature. | 0.501 |
Rv0802c | Rv1727 | Rv0802c | Rv1727 | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Rv1727, (MTCY04C12.12), len: 189 aa. Conserved hypothetical protein, similar to Mycobacterium tuberculosis hypothetical proteins P72040|Rv3773c|MTCY13D12.07C (194 aa), FASTA scores: opt: 176, E(): 2.7e-08, (31.1% identity in 180 aa overlap); and O53801|Rv0738 (182 aa). | 0.422 |
Rv0802c | Rv3225c | Rv0802c | Rv3225c | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | GCN5-related N-acetyltransferase, phosphorylase; Rv3225c, (MTCY07D11.01), len: 474 aa. Conserved hypothetical protein has GNAT (Gcn5-related N-acetyltransferase) domain in N-terminal part (see Vetting et al. 2005) and phosphotransferase domain in C-terminal part. C-terminal part shows similarity to various bacterial phosphotransferases e.g. BAB49093|MLL1809 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (298 aa),FASTA scores: opt: 557, E(): 2.8e-26, (34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA aminoglycoside 3'-phosphotransferase from Escherichia coli (271 [...] | 0.512 |
Rv0802c | Rv3660c | Rv0802c | Rv3660c | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Conserved hypothetical protein; May play a role in septum formation. | 0.416 |
Rv0802c | mbtG | Rv0802c | Rv2378c | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | 0.562 |
Rv0802c | purL | Rv0802c | Rv0803 | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Phosphoribosylformylglycinamidine synthase II PurL (FGAM synthase II); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.725 |
Rv0802c | rnc | Rv0802c | Rv2925c | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | Probable ribonuclease III Rnc (RNase III); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity). Belongs to the ribonuclease III family. | 0.542 |
Rv0804 | Rv0802c | Rv0804 | Rv0802c | Rv0804, (MTCY07H7A.05c), len: 209 aa. Conserved hypothetical protein, showing similarity with C-terminus of Rv1863c|MTCY359.10 conserved hypothetical protein from Mycobacterium tuberculosis (256 aa), FASTA scores: opt: 199, E(): 1.2e-05, (33.2% identity in 220 aa overlap); and Rv0658c. Contains PS01151 Fimbrial biogenesis outer membrane usher protein signature. | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.501 |
Rv0804 | mbtG | Rv0804 | Rv2378c | Rv0804, (MTCY07H7A.05c), len: 209 aa. Conserved hypothetical protein, showing similarity with C-terminus of Rv1863c|MTCY359.10 conserved hypothetical protein from Mycobacterium tuberculosis (256 aa), FASTA scores: opt: 199, E(): 1.2e-05, (33.2% identity in 220 aa overlap); and Rv0658c. Contains PS01151 Fimbrial biogenesis outer membrane usher protein signature. | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | 0.582 |
Rv0804 | purL | Rv0804 | Rv0803 | Rv0804, (MTCY07H7A.05c), len: 209 aa. Conserved hypothetical protein, showing similarity with C-terminus of Rv1863c|MTCY359.10 conserved hypothetical protein from Mycobacterium tuberculosis (256 aa), FASTA scores: opt: 199, E(): 1.2e-05, (33.2% identity in 220 aa overlap); and Rv0658c. Contains PS01151 Fimbrial biogenesis outer membrane usher protein signature. | Phosphoribosylformylglycinamidine synthase II PurL (FGAM synthase II); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL a [...] | 0.804 |
Rv1727 | Rv0802c | Rv1727 | Rv0802c | Rv1727, (MTCY04C12.12), len: 189 aa. Conserved hypothetical protein, similar to Mycobacterium tuberculosis hypothetical proteins P72040|Rv3773c|MTCY13D12.07C (194 aa), FASTA scores: opt: 176, E(): 2.7e-08, (31.1% identity in 180 aa overlap); and O53801|Rv0738 (182 aa). | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.422 |
Rv3225c | Rv0802c | Rv3225c | Rv0802c | GCN5-related N-acetyltransferase, phosphorylase; Rv3225c, (MTCY07D11.01), len: 474 aa. Conserved hypothetical protein has GNAT (Gcn5-related N-acetyltransferase) domain in N-terminal part (see Vetting et al. 2005) and phosphotransferase domain in C-terminal part. C-terminal part shows similarity to various bacterial phosphotransferases e.g. BAB49093|MLL1809 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (298 aa),FASTA scores: opt: 557, E(): 2.8e-26, (34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA aminoglycoside 3'-phosphotransferase from Escherichia coli (271 [...] | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.512 |
Rv3225c | mbtG | Rv3225c | Rv2378c | GCN5-related N-acetyltransferase, phosphorylase; Rv3225c, (MTCY07D11.01), len: 474 aa. Conserved hypothetical protein has GNAT (Gcn5-related N-acetyltransferase) domain in N-terminal part (see Vetting et al. 2005) and phosphotransferase domain in C-terminal part. C-terminal part shows similarity to various bacterial phosphotransferases e.g. BAB49093|MLL1809 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (298 aa),FASTA scores: opt: 557, E(): 2.8e-26, (34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA aminoglycoside 3'-phosphotransferase from Escherichia coli (271 [...] | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | 0.562 |
Rv3225c | rnc | Rv3225c | Rv2925c | GCN5-related N-acetyltransferase, phosphorylase; Rv3225c, (MTCY07D11.01), len: 474 aa. Conserved hypothetical protein has GNAT (Gcn5-related N-acetyltransferase) domain in N-terminal part (see Vetting et al. 2005) and phosphotransferase domain in C-terminal part. C-terminal part shows similarity to various bacterial phosphotransferases e.g. BAB49093|MLL1809 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (298 aa),FASTA scores: opt: 557, E(): 2.8e-26, (34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA aminoglycoside 3'-phosphotransferase from Escherichia coli (271 [...] | Probable ribonuclease III Rnc (RNase III); Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism (By similarity). Belongs to the ribonuclease III family. | 0.556 |
Rv3660c | Rv0802c | Rv3660c | Rv0802c | Conserved hypothetical protein; May play a role in septum formation. | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.416 |
mbtG | Rv0802c | Rv2378c | Rv0802c | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | Possible succinyltransferase in the GCN5-related N-acetyltransferase family; May function as a succinyl-CoA transferase. | 0.562 |
mbtG | Rv0804 | Rv2378c | Rv0804 | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | Rv0804, (MTCY07H7A.05c), len: 209 aa. Conserved hypothetical protein, showing similarity with C-terminus of Rv1863c|MTCY359.10 conserved hypothetical protein from Mycobacterium tuberculosis (256 aa), FASTA scores: opt: 199, E(): 1.2e-05, (33.2% identity in 220 aa overlap); and Rv0658c. Contains PS01151 Fimbrial biogenesis outer membrane usher protein signature. | 0.582 |
mbtG | Rv3225c | Rv2378c | Rv3225c | Lysine-N-oxygenase MbtG (L-lysine 6-monooxygenase) (lysine N6-hydroxylase); Flavoprotein monooxygenase required for N-hydroxylation of the two acylated lysine residues during mycobactin assembly, thus producing the hydroxamate groups necessary for iron sequestration. Is also able, but less efficiently, to hydroxylate L-lysine (non acylated) in vitro. | GCN5-related N-acetyltransferase, phosphorylase; Rv3225c, (MTCY07D11.01), len: 474 aa. Conserved hypothetical protein has GNAT (Gcn5-related N-acetyltransferase) domain in N-terminal part (see Vetting et al. 2005) and phosphotransferase domain in C-terminal part. C-terminal part shows similarity to various bacterial phosphotransferases e.g. BAB49093|MLL1809 hypothetical protein from Rhizobium loti (Mesorhizobium loti) (298 aa),FASTA scores: opt: 557, E(): 2.8e-26, (34.55% identity in 295 aa overlap); P14509|KKA8_ECOLI|APHA aminoglycoside 3'-phosphotransferase from Escherichia coli (271 [...] | 0.562 |