node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1192 | Rv1524 | Rv1192 | Rv1524 | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | 0.526 |
Rv1192 | Rv3179 | Rv1192 | Rv3179 | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | Conserved protein; Rv3179, (MTV014.23), len: 429 aa. Conserved protein,highly similar to Q9KH61 putative ATP/GTP binding protein from Mycobacterium smegmatis (428 aa), FASTA scores: opt: 2466, E(): 1.5e-148, (89.7% identity in 428 aa overlap) (no article found on the NCBI web site (July 2001)); and to other hypothetical bacterial proteins e.g. O07781|Rv0597c|MTCY19H5.25 from M. tuberculosis (411 aa),FASTA scores: opt: 1031, E(): 8e-58, (41.5% identity in 417 aa overlap); BAB54715|MLR9349 from Rhizobium loti (Mesorhizobium loti) (435 aa), FASTA scores: opt: 365, E(): 1.1e-15, (31.75% id [...] | 0.540 |
Rv1192 | Rv3351c | Rv1192 | Rv3351c | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | Rv3351c, (MTV004.08c), len: 264 aa. Hypothetical protein, highly similar to C-terminal region (aa 292-479) of O53608|Rv0063|MTV030.06 oxidoreductase from Mycobacterium tuberculosis (479 aa), FASTA scores: opt: 699, E(): 1.7e-36, (54.75% identity in 190 aa overlap). Shows some similarity to Q9KYD6|SCD72A.20 putative lipoprotein (fragment) from Streptomyces coelicolor (403 aa), FASTA scores: opt: 192, E(): 9.1e-05, (27.9% identity in 154 aa overlap); and P71091|YGAK hypothetical 54.4 KDA protein from Bacillus subtilis (480 aa), FASTA scores: opt: 174, E(): 0.0014, (26.5% identity in 166 [...] | 0.512 |
Rv1192 | Rv3651 | Rv1192 | Rv3651 | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | Rv3651, (MTCY15C10.01c), len: 345 aa. Hypothetical protein, with some similarity to Q9ZHK1 hypothetical 36.5 KDA protein from Rhodococcus sp. X309 (329 aa) FASTA scores: opt: 332, E(): 3.4e-13, (27.4% identity in 321 aa overlap). | 0.435 |
Rv1523 | Rv1524 | Rv1523 | Rv1524 | Probable methyltransferase; Rv1523, (MTCY19G5.05c), len: 347 aa (start uncertain). Probable methyltransferase, similar to G560513|U0002O Mycobacterium leprae (270 aa), FASTA scores: opt: 965, E(): 0, (60.3% identity in 247 aa overlap). Also similar to many e.g. Q54303|X86780 methyltransferase RAPM from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 323, E(): 1e-15, (41.2% identity in 136 aa overlap). And similar to M. tuberculosis hypothetical proteins Rv2952, Rv1405c, Rv1403c, Rv0839. | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | 0.898 |
Rv1523 | mmpL12 | Rv1523 | Rv1522c | Probable methyltransferase; Rv1523, (MTCY19G5.05c), len: 347 aa (start uncertain). Probable methyltransferase, similar to G560513|U0002O Mycobacterium leprae (270 aa), FASTA scores: opt: 965, E(): 0, (60.3% identity in 247 aa overlap). Also similar to many e.g. Q54303|X86780 methyltransferase RAPM from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 323, E(): 1e-15, (41.2% identity in 136 aa overlap). And similar to M. tuberculosis hypothetical proteins Rv2952, Rv1405c, Rv1403c, Rv0839. | Rv1522c, (MTCY19G5.06), len: 1146 aa. Probable mmpL12, conserved transmembrane transport protein (see Tekaia et al., 1999), member of RND superfamily. Strong similarity to many Mycobacterial membrane proteins e.g. Q49619|G466786 putative transport protein B1170_C1_181 from Mycobacterium leprae (1008 aa), FASTA scores: opt: 2418,E(): 0, (51.0% identity in 1006 aa overlap); etc. Also highly similar to MmpL8|MTCY48.08c|Rv3823c probable conserved transmembrane transport protein from Mycobacterium tuberculosis, FASTA score: (34.3% identity in 376 aa overlap); and some similarity to MmpL10|M [...] | 0.833 |
Rv1523 | wbbL2 | Rv1523 | Rv1525 | Probable methyltransferase; Rv1523, (MTCY19G5.05c), len: 347 aa (start uncertain). Probable methyltransferase, similar to G560513|U0002O Mycobacterium leprae (270 aa), FASTA scores: opt: 965, E(): 0, (60.3% identity in 247 aa overlap). Also similar to many e.g. Q54303|X86780 methyltransferase RAPM from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 323, E(): 1e-15, (41.2% identity in 136 aa overlap). And similar to M. tuberculosis hypothetical proteins Rv2952, Rv1405c, Rv1403c, Rv0839. | Rv1525, (MT1576, MTCY19G5.03c), len: 261 aa. Possible wbbL2, rhamnosyl transferase (see citation below),showing weak similarity to several rhamnosyl transferases. Similar to AF105060|AF105060_1 Riftia pachyptila endosymbiont (746 aa), FASTA scores: opt: 183, E(): 0.00013, (35.2% identity in 105 aa overlap). | 0.666 |
Rv1524 | Rv1192 | Rv1524 | Rv1192 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | 0.526 |
Rv1524 | Rv1523 | Rv1524 | Rv1523 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Probable methyltransferase; Rv1523, (MTCY19G5.05c), len: 347 aa (start uncertain). Probable methyltransferase, similar to G560513|U0002O Mycobacterium leprae (270 aa), FASTA scores: opt: 965, E(): 0, (60.3% identity in 247 aa overlap). Also similar to many e.g. Q54303|X86780 methyltransferase RAPM from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 323, E(): 1e-15, (41.2% identity in 136 aa overlap). And similar to M. tuberculosis hypothetical proteins Rv2952, Rv1405c, Rv1403c, Rv0839. | 0.898 |
Rv1524 | Rv3179 | Rv1524 | Rv3179 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Conserved protein; Rv3179, (MTV014.23), len: 429 aa. Conserved protein,highly similar to Q9KH61 putative ATP/GTP binding protein from Mycobacterium smegmatis (428 aa), FASTA scores: opt: 2466, E(): 1.5e-148, (89.7% identity in 428 aa overlap) (no article found on the NCBI web site (July 2001)); and to other hypothetical bacterial proteins e.g. O07781|Rv0597c|MTCY19H5.25 from M. tuberculosis (411 aa),FASTA scores: opt: 1031, E(): 8e-58, (41.5% identity in 417 aa overlap); BAB54715|MLR9349 from Rhizobium loti (Mesorhizobium loti) (435 aa), FASTA scores: opt: 365, E(): 1.1e-15, (31.75% id [...] | 0.515 |
Rv1524 | Rv3351c | Rv1524 | Rv3351c | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Rv3351c, (MTV004.08c), len: 264 aa. Hypothetical protein, highly similar to C-terminal region (aa 292-479) of O53608|Rv0063|MTV030.06 oxidoreductase from Mycobacterium tuberculosis (479 aa), FASTA scores: opt: 699, E(): 1.7e-36, (54.75% identity in 190 aa overlap). Shows some similarity to Q9KYD6|SCD72A.20 putative lipoprotein (fragment) from Streptomyces coelicolor (403 aa), FASTA scores: opt: 192, E(): 9.1e-05, (27.9% identity in 154 aa overlap); and P71091|YGAK hypothetical 54.4 KDA protein from Bacillus subtilis (480 aa), FASTA scores: opt: 174, E(): 0.0014, (26.5% identity in 166 [...] | 0.902 |
Rv1524 | Rv3651 | Rv1524 | Rv3651 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Rv3651, (MTCY15C10.01c), len: 345 aa. Hypothetical protein, with some similarity to Q9ZHK1 hypothetical 36.5 KDA protein from Rhodococcus sp. X309 (329 aa) FASTA scores: opt: 332, E(): 3.4e-13, (27.4% identity in 321 aa overlap). | 0.861 |
Rv1524 | mmpL12 | Rv1524 | Rv1522c | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Rv1522c, (MTCY19G5.06), len: 1146 aa. Probable mmpL12, conserved transmembrane transport protein (see Tekaia et al., 1999), member of RND superfamily. Strong similarity to many Mycobacterial membrane proteins e.g. Q49619|G466786 putative transport protein B1170_C1_181 from Mycobacterium leprae (1008 aa), FASTA scores: opt: 2418,E(): 0, (51.0% identity in 1006 aa overlap); etc. Also highly similar to MmpL8|MTCY48.08c|Rv3823c probable conserved transmembrane transport protein from Mycobacterium tuberculosis, FASTA score: (34.3% identity in 376 aa overlap); and some similarity to MmpL10|M [...] | 0.526 |
Rv1524 | papA1 | Rv1524 | Rv3824c | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Conserved polyketide synthase associated protein PapA1; Catalyzes the acylation of trehalose-2-sulfate-2'-palmitate (SL659) by adding the (hydroxy)phthioceranoyl group at the 3'-position to yield the diacylated intermediate 2-palmitoyl-3-(C43)-phthioceranyl- alpha, alpha'-D-trehalose-2'-sulfate (SL1278) during the cell wall sulfolipid-1 (SL-1) biosynthesis; Belongs to the PapA acyltransferase family. | 0.627 |
Rv1524 | papA2 | Rv1524 | Rv3820c | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Possible conserved polyketide synthase associated protein PapA2; Catalyzes the acylation of trehalose-2-sulfate by adding the palmitoyl group at the 2'-position to yield the intermediate trehalose- 2-sulfate-2'-palmitate (SL659) during the cell wall sulfolipid-1 (SL-1) biosynthesis; Belongs to the PapA acyltransferase family. | 0.619 |
Rv1524 | papA3 | Rv1524 | Rv1182 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Probable conserved polyketide synthase associated protein PapA3; Involved in the biosynthesis of polyacyltrehalose (PAT) which could have a role in anchoring the bacterial capsule. In vitro catalyzes the sequential transfer of two palmitoyl groups onto a single glucose residue of trehalose generating the diacylated product 2,3- diacyltrehalose (trehalose dipalmitate). Although palmitoyl-CoA (PCoA) seems to be the physiological acyl donor, PapA3 can also use docosanoyl (22-carbon saturated fatty acid) coenzyme A as acyl donor. | 0.636 |
Rv1524 | wbbL2 | Rv1524 | Rv1525 | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | Rv1525, (MT1576, MTCY19G5.03c), len: 261 aa. Possible wbbL2, rhamnosyl transferase (see citation below),showing weak similarity to several rhamnosyl transferases. Similar to AF105060|AF105060_1 Riftia pachyptila endosymbiont (746 aa), FASTA scores: opt: 183, E(): 0.00013, (35.2% identity in 105 aa overlap). | 0.751 |
Rv3179 | Rv1192 | Rv3179 | Rv1192 | Conserved protein; Rv3179, (MTV014.23), len: 429 aa. Conserved protein,highly similar to Q9KH61 putative ATP/GTP binding protein from Mycobacterium smegmatis (428 aa), FASTA scores: opt: 2466, E(): 1.5e-148, (89.7% identity in 428 aa overlap) (no article found on the NCBI web site (July 2001)); and to other hypothetical bacterial proteins e.g. O07781|Rv0597c|MTCY19H5.25 from M. tuberculosis (411 aa),FASTA scores: opt: 1031, E(): 8e-58, (41.5% identity in 417 aa overlap); BAB54715|MLR9349 from Rhizobium loti (Mesorhizobium loti) (435 aa), FASTA scores: opt: 365, E(): 1.1e-15, (31.75% id [...] | Unknown protein; Rv1192, (MTCI364.04), len: 275 aa. Unknown protein,contains PS00120 lipases, serine active site. | 0.540 |
Rv3179 | Rv1524 | Rv3179 | Rv1524 | Conserved protein; Rv3179, (MTV014.23), len: 429 aa. Conserved protein,highly similar to Q9KH61 putative ATP/GTP binding protein from Mycobacterium smegmatis (428 aa), FASTA scores: opt: 2466, E(): 1.5e-148, (89.7% identity in 428 aa overlap) (no article found on the NCBI web site (July 2001)); and to other hypothetical bacterial proteins e.g. O07781|Rv0597c|MTCY19H5.25 from M. tuberculosis (411 aa),FASTA scores: opt: 1031, E(): 8e-58, (41.5% identity in 417 aa overlap); BAB54715|MLR9349 from Rhizobium loti (Mesorhizobium loti) (435 aa), FASTA scores: opt: 365, E(): 1.1e-15, (31.75% id [...] | Rv1524, (MTCY19G5.04c), len: 414 aa. Probable glycosyltransferase, similar to many e.g. P96559|U84349 glycosyltransferase GTFB from Amycolatopsis orientalis (407 aa), FASTA scores: opt: 363, E(): 6.2e-23, (28.8% identity in 430 aa overlap); also high similarity to Rv1526c|MTCY19G5.02 Mycobacterium tuberculosis hypothetical protein (58.7% identity in 416 aa overlap); and AF143772|AF143772_15 glycosyltransferase gtfB from Mycobacterium avium strain 215 (418 aa), FASTA scores: opt: 1801, E(): 0, (65.2% identity in 417 aa overlap). | 0.515 |
Rv3179 | Rv3351c | Rv3179 | Rv3351c | Conserved protein; Rv3179, (MTV014.23), len: 429 aa. Conserved protein,highly similar to Q9KH61 putative ATP/GTP binding protein from Mycobacterium smegmatis (428 aa), FASTA scores: opt: 2466, E(): 1.5e-148, (89.7% identity in 428 aa overlap) (no article found on the NCBI web site (July 2001)); and to other hypothetical bacterial proteins e.g. O07781|Rv0597c|MTCY19H5.25 from M. tuberculosis (411 aa),FASTA scores: opt: 1031, E(): 8e-58, (41.5% identity in 417 aa overlap); BAB54715|MLR9349 from Rhizobium loti (Mesorhizobium loti) (435 aa), FASTA scores: opt: 365, E(): 1.1e-15, (31.75% id [...] | Rv3351c, (MTV004.08c), len: 264 aa. Hypothetical protein, highly similar to C-terminal region (aa 292-479) of O53608|Rv0063|MTV030.06 oxidoreductase from Mycobacterium tuberculosis (479 aa), FASTA scores: opt: 699, E(): 1.7e-36, (54.75% identity in 190 aa overlap). Shows some similarity to Q9KYD6|SCD72A.20 putative lipoprotein (fragment) from Streptomyces coelicolor (403 aa), FASTA scores: opt: 192, E(): 9.1e-05, (27.9% identity in 154 aa overlap); and P71091|YGAK hypothetical 54.4 KDA protein from Bacillus subtilis (480 aa), FASTA scores: opt: 174, E(): 0.0014, (26.5% identity in 166 [...] | 0.521 |