node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1944c | Rv1945 | Rv1944c | Rv1945 | Conserved protein; Rv1944c, (MTCY09F9.20), len: 196 aa. Conserved protein, similar to C-terminal part of SCE20.29|AL136058|CAB65585.1 hypothetical protein from Streptomyces coelicolor (338 aa), blastp scores, Identities = 37/131 (28%), Positives = 51/131 (38%). | Conserved hypothetical protein; Rv1945, (MTCY09F9.19c), len: 454 aa. Member of Mycobacterium tuberculosis REP13E12 repeat family. Similar to several others, best with Rv1148c|Z95584|MTCI65.15 (482 aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in 454 aa overlap). Contains possible helix-turn-helix motif at aa 74-95 (+2.90 SD). | 0.608 |
Rv1944c | mazE5 | Rv1944c | Rv1943c | Conserved protein; Rv1944c, (MTCY09F9.20), len: 196 aa. Conserved protein, similar to C-terminal part of SCE20.29|AL136058|CAB65585.1 hypothetical protein from Streptomyces coelicolor (338 aa), blastp scores, Identities = 37/131 (28%), Positives = 51/131 (38%). | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | 0.807 |
Rv1944c | mazF5 | Rv1944c | Rv1942c | Conserved protein; Rv1944c, (MTCY09F9.20), len: 196 aa. Conserved protein, similar to C-terminal part of SCE20.29|AL136058|CAB65585.1 hypothetical protein from Streptomyces coelicolor (338 aa), blastp scores, Identities = 37/131 (28%), Positives = 51/131 (38%). | Possible toxin MazF5; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE5. Probably an endoribonuclease (By similarity). | 0.802 |
Rv1945 | Rv1944c | Rv1945 | Rv1944c | Conserved hypothetical protein; Rv1945, (MTCY09F9.19c), len: 454 aa. Member of Mycobacterium tuberculosis REP13E12 repeat family. Similar to several others, best with Rv1148c|Z95584|MTCI65.15 (482 aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in 454 aa overlap). Contains possible helix-turn-helix motif at aa 74-95 (+2.90 SD). | Conserved protein; Rv1944c, (MTCY09F9.20), len: 196 aa. Conserved protein, similar to C-terminal part of SCE20.29|AL136058|CAB65585.1 hypothetical protein from Streptomyces coelicolor (338 aa), blastp scores, Identities = 37/131 (28%), Positives = 51/131 (38%). | 0.608 |
Rv1945 | mazE5 | Rv1945 | Rv1943c | Conserved hypothetical protein; Rv1945, (MTCY09F9.19c), len: 454 aa. Member of Mycobacterium tuberculosis REP13E12 repeat family. Similar to several others, best with Rv1148c|Z95584|MTCI65.15 (482 aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in 454 aa overlap). Contains possible helix-turn-helix motif at aa 74-95 (+2.90 SD). | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | 0.583 |
Rv1945 | mazF5 | Rv1945 | Rv1942c | Conserved hypothetical protein; Rv1945, (MTCY09F9.19c), len: 454 aa. Member of Mycobacterium tuberculosis REP13E12 repeat family. Similar to several others, best with Rv1148c|Z95584|MTCI65.15 (482 aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in 454 aa overlap). Contains possible helix-turn-helix motif at aa 74-95 (+2.90 SD). | Possible toxin MazF5; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE5. Probably an endoribonuclease (By similarity). | 0.582 |
mazE4 | mazE5 | Rv1494 | Rv1943c | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | 0.635 |
mazE4 | mazE7 | Rv1494 | Rv2063 | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Antitoxin MazE7; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli but not in M.smegmatis neutralizes the effect of cognate toxin MazF7. | 0.652 |
mazE4 | mazF5 | Rv1494 | Rv1942c | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible toxin MazF5; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE5. Probably an endoribonuclease (By similarity). | 0.404 |
mazE4 | vapB18 | Rv1494 | Rv2545 | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible antitoxin VapB18; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC18. | 0.656 |
mazE4 | vapB38 | Rv1494 | Rv2493 | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible antitoxin VapB38; Probable antitoxin component of a type II toxin-antitoxin (TA) system. Its putative cognate toxin is VapC38. | 0.550 |
mazE4 | vapB44 | Rv1494 | Rv3321c | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible antitoxin VapB44; Possibly the antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC44. | 0.527 |
mazE4 | vapC2 | Rv1494 | Rv0301 | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible toxin VapC2; Toxic component of a type II toxin-antitoxin (TA) system. Acts as an RNase. Upon expression in M.smegmatis inhibits translation, growth and colony formation. All its toxic effects are neutralized by coexpression with cognate antitoxin VapB2. | 0.517 |
mazE4 | vapC32 | Rv1494 | Rv1114 | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | Possible toxin VapC32. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB32.; Belongs to the PINc/VapC protein family. | 0.654 |
mazE5 | Rv1944c | Rv1943c | Rv1944c | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Conserved protein; Rv1944c, (MTCY09F9.20), len: 196 aa. Conserved protein, similar to C-terminal part of SCE20.29|AL136058|CAB65585.1 hypothetical protein from Streptomyces coelicolor (338 aa), blastp scores, Identities = 37/131 (28%), Positives = 51/131 (38%). | 0.807 |
mazE5 | Rv1945 | Rv1943c | Rv1945 | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Conserved hypothetical protein; Rv1945, (MTCY09F9.19c), len: 454 aa. Member of Mycobacterium tuberculosis REP13E12 repeat family. Similar to several others, best with Rv1148c|Z95584|MTCI65.15 (482 aa), FASTA score: opt: 2954, E(): 0, (97.1% identity in 454 aa overlap). Contains possible helix-turn-helix motif at aa 74-95 (+2.90 SD). | 0.583 |
mazE5 | mazE4 | Rv1943c | Rv1494 | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Possible antitoxin MazE4; Antitoxin component of a type II toxin-antitoxin (TA) system. In M.smegmatis neutralizes the toxic effect of mRNA interferase MazF4, its cognate toxin, on growth. | 0.635 |
mazE5 | mazE7 | Rv1943c | Rv2063 | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Antitoxin MazE7; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in E.coli but not in M.smegmatis neutralizes the effect of cognate toxin MazF7. | 0.760 |
mazE5 | mazF5 | Rv1943c | Rv1942c | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Possible toxin MazF5; Toxic component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin MazE5. Probably an endoribonuclease (By similarity). | 0.957 |
mazE5 | vapB18 | Rv1943c | Rv2545 | Possible antitoxin MazE5; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin MazF5. | Possible antitoxin VapB18; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC18. | 0.803 |