node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0061c | Rv1374c | Rv0061c | Rv1374c | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | 0.651 |
Rv0061c | Rv1954A | Rv0061c | Rv1954A | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | Rv1954A, len: 100 aa. Hypothetical unknown protein. | 0.651 |
Rv0061c | Rv1954c | Rv0061c | Rv1954c | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | 0.652 |
Rv0061c | Rv2660c | Rv0061c | Rv2660c | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.660 |
Rv0188 | Rv1954c | Rv0188 | Rv1954c | Rv0188, (MTCI28.27), len: 143 aa. Probable conserved transmembrane protein, similar to T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable membrane protein from Streptomyces coelicolor (147 aa),FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in 141 aa overlap); N-terminus of P80185|MTRC_METTH tetrahydromethanopterin S-methyltransferase subunit C from Methanobacterium thermoautotrophicum strain Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E(): 0.033, (31.6% identity in 98 aa overlap). Also similar to Rv3635 from Mycobacterium tuberculosis. | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | 0.483 |
Rv0188 | Rv2660c | Rv0188 | Rv2660c | Rv0188, (MTCI28.27), len: 143 aa. Probable conserved transmembrane protein, similar to T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable membrane protein from Streptomyces coelicolor (147 aa),FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in 141 aa overlap); N-terminus of P80185|MTRC_METTH tetrahydromethanopterin S-methyltransferase subunit C from Methanobacterium thermoautotrophicum strain Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E(): 0.033, (31.6% identity in 98 aa overlap). Also similar to Rv3635 from Mycobacterium tuberculosis. | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.535 |
Rv0188 | Rv3661 | Rv0188 | Rv3661 | Rv0188, (MTCI28.27), len: 143 aa. Probable conserved transmembrane protein, similar to T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable membrane protein from Streptomyces coelicolor (147 aa),FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in 141 aa overlap); N-terminus of P80185|MTRC_METTH tetrahydromethanopterin S-methyltransferase subunit C from Methanobacterium thermoautotrophicum strain Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E(): 0.033, (31.6% identity in 98 aa overlap). Also similar to Rv3635 from Mycobacterium tuberculosis. | Rv3661, (MTV025.009), len: 287 aa. Conserved hypothetical protein, highly similar to O33611|IMD_STRCN from Streptomyces cyaneus (Streptomyces curacoi) protein involved in inhibition of morphological differentiation in Streptomyces azureus (belongs to the SerB family) (277 aa) FASTA scores: opt: 1073, E(): 3.5e-61, (61.45% identity in 262 aa overlap); and Q9X923|SCH5.21 putative morphological differentiation-associated protein from Streptomyces coelicolor (268 aa), FASTA scores: opt: 1057, E(): 3.6e-60,(61.45% identity in 262 aa overlap). Also similar to various bacterial proteins (prin [...] | 0.438 |
Rv0188 | usfY | Rv0188 | Rv3288c | Rv0188, (MTCI28.27), len: 143 aa. Probable conserved transmembrane protein, similar to T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable membrane protein from Streptomyces coelicolor (147 aa),FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in 141 aa overlap); N-terminus of P80185|MTRC_METTH tetrahydromethanopterin S-methyltransferase subunit C from Methanobacterium thermoautotrophicum strain Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E(): 0.033, (31.6% identity in 98 aa overlap). Also similar to Rv3635 from Mycobacterium tuberculosis. | Putative protein UsfY; Rv3288c, (MTCY71.28c), len: 137 aa. UsfY, putative protein (see citation below). Has no significant homologues. May not be contranscribed with the usfX and sigF proteins. | 0.639 |
Rv1374c | Rv0061c | Rv1374c | Rv0061c | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | 0.651 |
Rv1374c | Rv1954A | Rv1374c | Rv1954A | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | Rv1954A, len: 100 aa. Hypothetical unknown protein. | 0.513 |
Rv1374c | Rv1954c | Rv1374c | Rv1954c | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | 0.521 |
Rv1374c | Rv2660c | Rv1374c | Rv2660c | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.562 |
Rv1954A | Rv0061c | Rv1954A | Rv0061c | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | 0.651 |
Rv1954A | Rv1374c | Rv1954A | Rv1374c | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Hypothetical protein; Rv1374c, (MTCY02B12.08c), len: 152 aa. Hypothetical unknown protein. | 0.513 |
Rv1954A | Rv1954c | Rv1954A | Rv1954c | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | 0.540 |
Rv1954A | Rv2660c | Rv1954A | Rv2660c | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Hypothetical protein; Rv2660c, (MTCY441.29c), len: 75 aa (questionable orf). Hypothetical unknown protein. | 0.572 |
Rv1954A | higB | Rv1954A | Rv1955 | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Possible toxin HigB; Toxic component of an atypical, type II toxin-antitoxin chaperone (TAC) system. Upon expression in M.smegmatis inhibits colony formation and cell growth. Ectopic expression in wild-type M.tuberculosis has no effect on cell growth; ectopic expression in a triple higB1-higA1-Rv1957 (delta TAC) disruption mutant causes growth arrest, killing a considerable proportion of the cells. Increased ectopic expression leads to decreased levels of IdeR- and Zur-regulated genes as well as cleavage within the mRNA region of tmRNA (transfer-mRNA), strongly suggesting it is an endo [...] | 0.618 |
Rv1954A | secBL | Rv1954A | Rv1957 | Rv1954A, len: 100 aa. Hypothetical unknown protein. | Hypothetical protein; Chaperone component of an atypical, type II toxin-antitoxin chaperone (TAC) system. Prevents antitoxin HigA1 aggregation in vitro at a 1:3 chaperone:antitoxin ratio, probably also protects antitoxin HigA1 from protease. Required for neutralization of toxin HigB1 upon ectopic expression in Mycobacterium marinum or E.coli. When expressed in E.coli complements a secB deletion, restores export of OmpA and MBP and inhibits aggregation of proOmpC although it is less efficient than endogenous SecB. Complements the general chaperone function of E.coli SecB less well; Belo [...] | 0.661 |
Rv1954c | Rv0061c | Rv1954c | Rv0061c | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | Hypothetical protein; Rv0061c, len: 112 aa. Conserved hypothetical protein supported by RNA-seq data. Similar to MMAR_3839, 76% identity in 112 aa overlap. Replaces questionable ORF Rv0061 (MTV030.04). | 0.652 |
Rv1954c | Rv0188 | Rv1954c | Rv0188 | Hypothetical protein; Rv1954c, (MTCY09F9.10), len: 173 aa. Hypothetical unknown protein, end overlaps next ORF upstream, Rv1955 (MTCY09F9.09c). | Rv0188, (MTCI28.27), len: 143 aa. Probable conserved transmembrane protein, similar to T35347|4835334|CAB42956.1|AL049863|SC5H1_31 probable membrane protein from Streptomyces coelicolor (147 aa),FASTA scores: opt: 326, E(): 6.5e-15, (36.2% identity in 141 aa overlap); N-terminus of P80185|MTRC_METTH tetrahydromethanopterin S-methyltransferase subunit C from Methanobacterium thermoautotrophicum strain Marburg/DSM 2133 (266 aa), FASTA scores: opt: 125, E(): 0.033, (31.6% identity in 98 aa overlap). Also similar to Rv3635 from Mycobacterium tuberculosis. | 0.483 |