STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rv2083Rv2083, (MTCY49.22), len: 314 aa. Conserved hypothetical protein. Similar to many e.g. Mycobacterium tuberculosis Rv3898c (110 aa) and Rv3897c (210 aa). (314 aa)    
Predicted Functional Partners:
Rv2084
Hypothetical protein; Rv2084, (MTCY49.23), len: 378 aa. Hypothetical unknown protein. This region is a possible MT-complex-specific genomic island (See Becq et al.,2007).
  
    0.853
Rv2082
Rv2082, (MTCY49.21), len: 721 aa. Conserved hypothetical protein. Similar to Mycobacterium tuberculosis Rv0029, and to Rv3899c and Rv3900c which may be frameshifted.
  
    0.827
eccB3
ESX conserved component EccB3. ESX-3 type VII secretion system protein. Possible membrane protein; An ATPase (By similarity). Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.; Belongs to the EccB family.
  
  
 0.648
eccD3
ESX-3 secretion system protein EccD3; Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
   
  
 0.633
mycP3
Mycosin-3; Rv0291, (MTV035.19), len: 461 aa. Probable mycP3,membrane-anchored serine protease (mycosin) (see Brown et al., 2000), similar to several others in mycobacteria e.g. Z94121|MTY15F10_28|Rv1796 from Mycobacterium tuberculosis (446 aa), FASTA scores: opt: 1168, E(): 0, (44.6% identity in 453 aa overlap); Rv3886c; Rv3883c; Rv3449; and Y14967|MLCB628_4|MLCB628.04 from Mycobacterium leprae (446 aa), FASTA scores: opt: 1159, E(): 0, (43.5 identity in 446 aa overlap). Has signal sequence and hydrophobic stretch at C-terminus, followed by short positively charged segment,that seems t [...]
  
  
 0.591
Rv2085
Rv2085, (MTCY49.24), len: 101 aa. Conserved hypothetical protein, similar to but shorter than many transposases but we can find no sequence errors to account for the frameshifts. Contains possible helix-turn-helix motif at aa 33 to 54,(+3.11 SD). This region is a possible MT-complex-specific genomic island (See Becq et al.,2007).
  
    0.571
eccC3
ESX conserved component EccC3. ESX-3 type VII secretion system protein. Possible membrane protein; Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis.
   
  
 0.559
eccE3
ESX-3 secretion system protein EccE3; Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis. Belongs to the EccE family.
   
  
 0.556
Rv2086
Rv2086, (MTCY49.25), len: 201 aa. Conserved hypothetical protein, similarity to but shorter than many transposases but we can find no sequence errors to account for the frameshifts. Start changed since first submission (-16 aa). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007).
  
    0.556
eccA3
ESX conserved component EccA3. ESX-3 type VII secretion system protein; Part of the ESX-3 specialized secretion system, which is important for iron and zinc uptake or homeostasis. EccA3 exhibits ATPase activity and may provide energy for the export of ESX-3 substrates (By similarity). Belongs to the CbxX/CfxQ family.
   
  
 0.549
Your Current Organism:
Mycobacterium tuberculosis H37Rv
NCBI taxonomy Id: 83332
Other names: M. tuberculosis H37Rv, Mycobacterium sp. H37Rv, Mycobacterium tuberculosis str. H37Rv, Mycobacterium tuberculosis strain H37Rv
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