node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv1459c | Rv2179c | Rv1459c | Rv2179c | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | 0.424 |
Rv1459c | Rv2181 | Rv1459c | Rv2181 | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | 0.747 |
Rv1459c | aftB | Rv1459c | Rv3805c | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | 0.829 |
Rv1459c | aftD | Rv1459c | Rv0236c | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Possible arabinofuranosyltransferase AftD; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.759 |
Rv1459c | embC | Rv1459c | Rv3793 | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Probable arabinosyltransferase C; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. | 0.691 |
Rv1459c | mptA | Rv1459c | Rv2174 | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | Alpha(1->6)mannosyltransferase. Possible conserved integral membrane protein; Involved in the latter stages of the biosynthesis of the alpha-(1->6) mannan core of lipomannan (LM). Catalyzes the addition of alpha-(1->6)-mannose residue.; Belongs to the MptA/B family. | 0.948 |
Rv1635c | Rv2181 | Rv1635c | Rv2181 | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | 0.934 |
Rv1635c | aftB | Rv1635c | Rv3805c | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Possible arabinofuranosyltransferase AftB; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the transfer of arabinofuranosyl (Araf) residues from the sugar donor decaprenyl-phospho-arabinose (DPA) to the arabinan domain to form terminal beta-(1->2)-linked Araf residues, which marks the end point for AG arabinan biosynthesis before decoration with mycolic acids. | 0.744 |
Rv1635c | aftD | Rv1635c | Rv0236c | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Possible arabinofuranosyltransferase AftD; Involved in the biosynthesis of the arabinogalactan (AG) region of the mycolylarabinogalactan-peptidoglycan (mAGP) complex, an essential component of the mycobacterial cell wall. Catalyzes the addition of an arabinofuranosyl (Araf) residue from the sugar donor decaprenyl-phospho-arabinose (DPA) on the C-3 of an alpha-(1->5)-linked Araf from the arabinan backbone of AG. | 0.412 |
Rv1635c | embC | Rv1635c | Rv3793 | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable arabinosyltransferase C; Arabinosyl transferase responsible for the polymerization of arabinose into the arabinan of arabinogalactan. | 0.606 |
Rv1635c | mptA | Rv1635c | Rv2174 | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Alpha(1->6)mannosyltransferase. Possible conserved integral membrane protein; Involved in the latter stages of the biosynthesis of the alpha-(1->6) mannan core of lipomannan (LM). Catalyzes the addition of alpha-(1->6)-mannose residue.; Belongs to the MptA/B family. | 0.816 |
Rv2179c | Rv1459c | Rv2179c | Rv1459c | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | 0.424 |
Rv2179c | Rv2180c | Rv2179c | Rv2180c | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | Rv2180c, (MTV021.13c), len: 295 aa. Probable conserved integral membrane protein, similar to pir||T35292 probable integral membrane protein from Streptomyces coelicolor >gi|5578858|emb|CAB51260.1| (AL096872) (246 aa) (36% identity in 249 aa overlap). | 0.884 |
Rv2179c | Rv2181 | Rv2179c | Rv2181 | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | 0.805 |
Rv2179c | aroG | Rv2179c | Rv2178c | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | Phospho-2-dehydro-3-deoxyheptonate aldolase AroG; Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate. | 0.789 |
Rv2180c | Rv2179c | Rv2180c | Rv2179c | Rv2180c, (MTV021.13c), len: 295 aa. Probable conserved integral membrane protein, similar to pir||T35292 probable integral membrane protein from Streptomyces coelicolor >gi|5578858|emb|CAB51260.1| (AL096872) (246 aa) (36% identity in 249 aa overlap). | Conserved hypothetical protein; Exonuclease that cleaves single-stranded 3' overhangs of double-stranded RNA. Has no activity with 5' overhangs. Has negligible endonuclease activity. Can bind ATP, dATP and AMP (in vitro); the nucleotide occupies the predicted substrate binding site. | 0.884 |
Rv2180c | Rv2181 | Rv2180c | Rv2181 | Rv2180c, (MTV021.13c), len: 295 aa. Probable conserved integral membrane protein, similar to pir||T35292 probable integral membrane protein from Streptomyces coelicolor >gi|5578858|emb|CAB51260.1| (AL096872) (246 aa) (36% identity in 249 aa overlap). | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | 0.785 |
Rv2180c | aroG | Rv2180c | Rv2178c | Rv2180c, (MTV021.13c), len: 295 aa. Probable conserved integral membrane protein, similar to pir||T35292 probable integral membrane protein from Streptomyces coelicolor >gi|5578858|emb|CAB51260.1| (AL096872) (246 aa) (36% identity in 249 aa overlap). | Phospho-2-dehydro-3-deoxyheptonate aldolase AroG; Catalyzes an aldol-like condensation reaction between phosphoenolpyruvate (PEP) and D-erythrose 4-phosphate (E4P) to generate 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAH7P) and inorganic phosphate. | 0.778 |
Rv2181 | Rv1459c | Rv2181 | Rv1459c | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | Possible conserved integral membrane protein; Catalyzes the addition of alpha-(1->6)-mannose residue. Belongs to the MptA/B family. | 0.747 |
Rv2181 | Rv1635c | Rv2181 | Rv1635c | Alpha(1->2)mannosyltransferase; Responsible for the addition of alpha-(1-2) mannose branches to the linear mannan core on the biosynthetic pathway to mature lipoarabinomannan (LAM). | Probable mannosyltransferase. Probable conserved transmembrane protein; Rv1635c, (MTCY01B2.27c), len: 556 aa. Probable mannosyltransferase (See Dinadayala et al., 2006). Predicted to be in the GT-C superfamily of glycosyltransferases (See Liu and Mushegian, 2003). Probable conserved transmembrane protein, equivalent to CAC31770.1|AL583921 Mycobacterium leprae membrane protein (527 aa), Identities = 332/527 (62%). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.934 |