node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv2876 | ctaC | Rv2876 | Rv2200c | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | 0.999 |
Rv2876 | ctaD | Rv2876 | Rv3043c | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity). | 0.999 |
Rv2876 | ctaE | Rv2876 | Rv2193 | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Rv2193, (MTCY190.04), len: 203 aa. Probable ctaE,cytochrome c oxidase polypeptide III (cox3), with strong similarity to others e.g. COX3_SYNY3|Q06475 (29.8% identity in 225 aa overlap). | 0.999 |
Rv2876 | ctaF | Rv2876 | Rv2199c | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Possible conserved integral membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. | 0.999 |
Rv2876 | qcrA | Rv2876 | Rv2195 | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable rieske iron-sulfur protein QcrA; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. | 0.999 |
Rv2876 | qcrB | Rv2876 | Rv2196 | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit); Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site. | 0.999 |
Rv2876 | qcrC | Rv2876 | Rv2194 | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit); Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. | 0.999 |
Rv2876 | sodC | Rv2876 | Rv0432 | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Periplasmic superoxide dismutase [Cu-Zn] SodC; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. May play a role in favoring mycobacterial survival in phagocytes (By similarity). | 0.997 |
atpH | ctaC | Rv1307 | Rv2200c | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | 0.726 |
atpH | ctaD | Rv1307 | Rv3043c | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity). | 0.788 |
atpH | ctaE | Rv1307 | Rv2193 | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Rv2193, (MTCY190.04), len: 203 aa. Probable ctaE,cytochrome c oxidase polypeptide III (cox3), with strong similarity to others e.g. COX3_SYNY3|Q06475 (29.8% identity in 225 aa overlap). | 0.651 |
atpH | pepR | Rv1307 | Rv2782c | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Rv2782c, (MTV002.47c), len: 438 aa. Probable pepR,protease/peptidase, equivalent to O32965|YR82_MYCLE|ML0855|MLCB22.26c hypothetical zinc protease from Mycobacterium leprae (445 aa), FASTA scores: opt: 2346, E(): 4.3e-146, (84.3% identity in 421 aa overlap). Also highly similar to others e.g. O86835|YA12_STRCO|SC9A10.02 from Streptomyces coelicolor (459 aa), FASTA scores: opt: 1394, E(): 1.1e-83, (51.9% identity in 416 aa overlap); Q04805|YMXG_BACSU|YMXG from Bacillus subtilis (409 aa), FASTA scores: opt: 1014, E(): 7.9e-59, (37.55% identity in 410 aa overlap); Q9KA85|BH2405 from Bacil [...] | 0.834 |
atpH | qcrA | Rv1307 | Rv2195 | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Probable rieske iron-sulfur protein QcrA; Iron-sulfur subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of menaquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. | 0.987 |
atpH | qcrB | Rv1307 | Rv2196 | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Probable ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit); Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. The cytochrome b subunit contains two ubiquinol reactive sites: the oxidation (QP) site and the reduction (QN) site. | 0.942 |
atpH | qcrC | Rv1307 | Rv2194 | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | Probable ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit); Cytochrome b subunit of the cytochrome bc1 complex, an essential component of the respiratory electron transport chain required for ATP synthesis. The bc1 complex catalyzes the oxidation of ubiquinol and the reduction of cytochrome c in the respiratory chain. The bc1 complex operates through a Q-cycle mechanism that couples electron transfer to generation of the proton gradient that drives ATP synthesis. | 0.494 |
ctaC | Rv2876 | Rv2200c | Rv2876 | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | Rv2876, (MTCY274.07), len: 104 aa. Possible conserved transmembrane protein, equivalent (but longer 16 aa) to Q9CBU2|ML1584 possible conserved membrane protein from Mycobacterium leprae (84 aa), FASTA scores: opt: 444,E(): 8.3e-26, (73.85% identity in 88 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.999 |
ctaC | atpH | Rv2200c | Rv1307 | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | Probable ATP synthase delta chain AtpH; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (By similarity). In the C-terminal section; belongs to the ATPase delta chain family. | 0.726 |
ctaC | ctaD | Rv2200c | Rv3043c | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | Probable cytochrome C oxidase polypeptide I CtaD (cytochrome AA3 subunit 1); Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits 1-3 form the functional core of the enzyme complex. CO I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit 2 and heme A of subunit 1 to the bimetallic center formed by heme A3 and copper B (By similarity). | 0.999 |
ctaC | ctaE | Rv2200c | Rv2193 | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | Rv2193, (MTCY190.04), len: 203 aa. Probable ctaE,cytochrome c oxidase polypeptide III (cox3), with strong similarity to others e.g. COX3_SYNY3|Q06475 (29.8% identity in 225 aa overlap). | 0.999 |
ctaC | ctaF | Rv2200c | Rv2199c | Probable transmembrane cytochrome C oxidase (subunit II) CtaC; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) (By similarity). | Possible conserved integral membrane protein; Part of cytochrome c oxidase, its function is unknown. Belongs to the cytochrome c oxidase bacterial subunit CtaF family. | 0.999 |