node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PE23 | Rv1691 | Rv2328 | Rv1691 | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Rv1691, MTCI125.13, len: 250 aa. Conserved hypothetical protein, similar to Q9S210|SCI51.30C|AL109848 Hypothetical protein from Streptomyces coelicolor (210 aa),FASTA score: opt: 556, E(): 6.4e-27, (50.6% identity in 180 aa overlap). | 0.778 |
PE23 | Rv2133c | Rv2328 | Rv2133c | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Rv2133c, (MTCY270.35), len: 262 aa. Conserved hypothetical protein. Function: unknown but equivalent to hypothetical Mycobacterium leprae protein, Q49774. FASTA best: Q49774 B2126_C1_150 (262 aa) opt: 1447, E(): 0; (79.0% identity in 262 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | 0.871 |
PE23 | Rv3529c | Rv2328 | Rv3529c | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Rv3529c, (MTCY03C7.27), len: 384 aa. Conserved hypothetical protein, showing some similarity to Q50695|YM67_MYCTU|Rv2267c|MT2329|MTCY339.43 hypothetical 46.1 KDA protein from Mycobacterium tuberculosis (388 aa) FASTA scores: opt: 261, E(): 1.6e-09, (27.25% identity in 253 aa overlap). | 0.778 |
PE23 | alaS | Rv2328 | Rv2555c | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.848 |
PE23 | helZ | Rv2328 | Rv2101 | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Probable helicase HelZ; Rv2101, (MTV020.01), len: 1013 aa. Probable helZ,helicase, similar to many. Nucleotide position 2361623 in the genome sequence has been corrected, A:C resulting in M462L. | 0.779 |
PE23 | rplF | Rv2328 | Rv0719 | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | 50S ribosomal protein L6 RplF; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. | 0.743 |
PE23 | rplJ | Rv2328 | Rv0651 | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | 50S ribosomal protein L10 RplJ; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. | 0.746 |
PE23 | rpmD | Rv2328 | Rv0722 | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Rv0722, (MTCY210.41), len: 65 aa. rpmD, 50S ribosomal protein L30, equivalent to O33001 ribosomal protein L30 from Mycobacterium leprae (71 aa). Also highly similar to others e.g. P46789|RL30_STRCO 50S ribosomal protein L30 from Streptomyces coelicolor (60 aa); P02430|RL30_ECOLI 50S ribosomal protein L30 from Escherichia coli (58 aa), FASTA scores: opt: 168, E(): 1.5e-13, (53.7% identity in 54 aa overlap); etc. Belongs to the L30P family of ribosomal proteins. | 0.740 |
PE23 | rpoA | Rv2328 | Rv3457c | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.747 |
PE23 | stf3 | Rv2328 | Rv2267c | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | Conserved hypothetical protein; Required for the sulfation of S881. S881 is a sulfated menaquinone, which is localized in the outer envelope of M.tuberculosis and negatively regulates its virulence. 3'-phosphoadenosine-5'- phosphosulfate (PAPS) is the sulfate donor. Belongs to the Stf3 family. | 0.817 |
Rv1691 | PE23 | Rv1691 | Rv2328 | Rv1691, MTCI125.13, len: 250 aa. Conserved hypothetical protein, similar to Q9S210|SCI51.30C|AL109848 Hypothetical protein from Streptomyces coelicolor (210 aa),FASTA score: opt: 556, E(): 6.4e-27, (50.6% identity in 180 aa overlap). | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | 0.778 |
Rv1691 | alaS | Rv1691 | Rv2555c | Rv1691, MTCI125.13, len: 250 aa. Conserved hypothetical protein, similar to Q9S210|SCI51.30C|AL109848 Hypothetical protein from Streptomyces coelicolor (210 aa),FASTA score: opt: 556, E(): 6.4e-27, (50.6% identity in 180 aa overlap). | Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.925 |
Rv1691 | helZ | Rv1691 | Rv2101 | Rv1691, MTCI125.13, len: 250 aa. Conserved hypothetical protein, similar to Q9S210|SCI51.30C|AL109848 Hypothetical protein from Streptomyces coelicolor (210 aa),FASTA score: opt: 556, E(): 6.4e-27, (50.6% identity in 180 aa overlap). | Probable helicase HelZ; Rv2101, (MTV020.01), len: 1013 aa. Probable helZ,helicase, similar to many. Nucleotide position 2361623 in the genome sequence has been corrected, A:C resulting in M462L. | 0.749 |
Rv1691 | rpoA | Rv1691 | Rv3457c | Rv1691, MTCI125.13, len: 250 aa. Conserved hypothetical protein, similar to Q9S210|SCI51.30C|AL109848 Hypothetical protein from Streptomyces coelicolor (210 aa),FASTA score: opt: 556, E(): 6.4e-27, (50.6% identity in 180 aa overlap). | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.878 |
Rv2133c | PE23 | Rv2133c | Rv2328 | Rv2133c, (MTCY270.35), len: 262 aa. Conserved hypothetical protein. Function: unknown but equivalent to hypothetical Mycobacterium leprae protein, Q49774. FASTA best: Q49774 B2126_C1_150 (262 aa) opt: 1447, E(): 0; (79.0% identity in 262 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | 0.871 |
Rv2133c | helZ | Rv2133c | Rv2101 | Rv2133c, (MTCY270.35), len: 262 aa. Conserved hypothetical protein. Function: unknown but equivalent to hypothetical Mycobacterium leprae protein, Q49774. FASTA best: Q49774 B2126_C1_150 (262 aa) opt: 1447, E(): 0; (79.0% identity in 262 aa overlap). A core mycobacterial gene; conserved in mycobacterial strains (See Marmiesse et al., 2004). | Probable helicase HelZ; Rv2101, (MTV020.01), len: 1013 aa. Probable helZ,helicase, similar to many. Nucleotide position 2361623 in the genome sequence has been corrected, A:C resulting in M462L. | 0.922 |
Rv3529c | PE23 | Rv3529c | Rv2328 | Rv3529c, (MTCY03C7.27), len: 384 aa. Conserved hypothetical protein, showing some similarity to Q50695|YM67_MYCTU|Rv2267c|MT2329|MTCY339.43 hypothetical 46.1 KDA protein from Mycobacterium tuberculosis (388 aa) FASTA scores: opt: 261, E(): 1.6e-09, (27.25% identity in 253 aa overlap). | Rv2328, (MTCY3G12.06), len: 382 aa. PE23, Member of the Mycobacterium tuberculosis PE family (see citation below), similar to others e.g. Q9L8K5|MAG24-1 PE-PGRS homolog from Mycobacterium marinum (638 aa), FASTA scores: opt: 495, E(): 6.6e-18, (34.65% identity in 401 aa overlap); etc. | 0.778 |
Rv3529c | alaS | Rv3529c | Rv2555c | Rv3529c, (MTCY03C7.27), len: 384 aa. Conserved hypothetical protein, showing some similarity to Q50695|YM67_MYCTU|Rv2267c|MT2329|MTCY339.43 hypothetical 46.1 KDA protein from Mycobacterium tuberculosis (388 aa) FASTA scores: opt: 261, E(): 1.6e-09, (27.25% identity in 253 aa overlap). | Probable alanyl-tRNA synthetase AlaS (alanine--tRNA ligase) (alanine translase) (ALARS); Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain; Belongs to the class-II aminoacyl-tRNA synthetase family. | 0.925 |
Rv3529c | helZ | Rv3529c | Rv2101 | Rv3529c, (MTCY03C7.27), len: 384 aa. Conserved hypothetical protein, showing some similarity to Q50695|YM67_MYCTU|Rv2267c|MT2329|MTCY339.43 hypothetical 46.1 KDA protein from Mycobacterium tuberculosis (388 aa) FASTA scores: opt: 261, E(): 1.6e-09, (27.25% identity in 253 aa overlap). | Probable helicase HelZ; Rv2101, (MTV020.01), len: 1013 aa. Probable helZ,helicase, similar to many. Nucleotide position 2361623 in the genome sequence has been corrected, A:C resulting in M462L. | 0.748 |
Rv3529c | rpoA | Rv3529c | Rv3457c | Rv3529c, (MTCY03C7.27), len: 384 aa. Conserved hypothetical protein, showing some similarity to Q50695|YM67_MYCTU|Rv2267c|MT2329|MTCY339.43 hypothetical 46.1 KDA protein from Mycobacterium tuberculosis (388 aa) FASTA scores: opt: 261, E(): 1.6e-09, (27.25% identity in 253 aa overlap). | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.877 |