node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
argD | argR | Rv1655 | Rv1657 | Rv1655, (MTCY06H11.20), len: 400 aa. Probable argD,Acetylornithine aminotransferase, similar to ARGD_ECOLI|P18335 (406 aa), FASTA scores: opt: 958, E(): 0,(38.6% identity in 404 aa overlap), contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases. | Probable arginine repressor ArgR (AHRC); Regulates arginine biosynthesis genes. | 0.998 |
argD | vapB17 | Rv1655 | Rv2526 | Rv1655, (MTCY06H11.20), len: 400 aa. Probable argD,Acetylornithine aminotransferase, similar to ARGD_ECOLI|P18335 (406 aa), FASTA scores: opt: 958, E(): 0,(38.6% identity in 404 aa overlap), contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases. | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | 0.513 |
argD | vapB31 | Rv1655 | Rv0748 | Rv1655, (MTCY06H11.20), len: 400 aa. Probable argD,Acetylornithine aminotransferase, similar to ARGD_ECOLI|P18335 (406 aa), FASTA scores: opt: 958, E(): 0,(38.6% identity in 404 aa overlap), contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases. | Possible antitoxin VapB31; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC31. | 0.510 |
argR | argD | Rv1657 | Rv1655 | Probable arginine repressor ArgR (AHRC); Regulates arginine biosynthesis genes. | Rv1655, (MTCY06H11.20), len: 400 aa. Probable argD,Acetylornithine aminotransferase, similar to ARGD_ECOLI|P18335 (406 aa), FASTA scores: opt: 958, E(): 0,(38.6% identity in 404 aa overlap), contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases. | 0.998 |
argR | vapB17 | Rv1657 | Rv2526 | Probable arginine repressor ArgR (AHRC); Regulates arginine biosynthesis genes. | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | 0.443 |
argR | vapB31 | Rv1657 | Rv0748 | Probable arginine repressor ArgR (AHRC); Regulates arginine biosynthesis genes. | Possible antitoxin VapB31; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC31. | 0.439 |
mazF8 | vapB17 | Rv2274c | Rv2526 | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | 0.511 |
mazF8 | vapC10 | Rv2274c | Rv1397c | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible toxin VapC10; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB10 (By similarity). Belongs to the PINc/VapC protein family. | 0.520 |
mazF8 | vapC12 | Rv2274c | Rv1720c | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible toxin VapC12; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB12 (By similarity). Belongs to the PINc/VapC protein family. | 0.523 |
mazF8 | vapC3 | Rv2274c | Rv0549c | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible toxin VapC3; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB3. | 0.432 |
mazF8 | vapC47 | Rv2274c | Rv3408 | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible toxin VapC47. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits translation and colony formation. Its toxic effect on colony formation is neutralized by coexpression with cognate antitoxin VapB47; the effect on translation has not been tested but is probably neutralized also.; Belongs to the PINc/VapC protein family. | 0.510 |
mazF8 | vapC6 | Rv2274c | Rv0656c | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | Possible toxin VapC6; Toxic component of a type II type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB6 (By similarity). Belongs to the PINc/VapC protein family. | 0.575 |
vapB17 | argD | Rv2526 | Rv1655 | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Rv1655, (MTCY06H11.20), len: 400 aa. Probable argD,Acetylornithine aminotransferase, similar to ARGD_ECOLI|P18335 (406 aa), FASTA scores: opt: 958, E(): 0,(38.6% identity in 404 aa overlap), contains PS00600 Aminotransferases class-III pyridoxal-phosphate attachment site. Belongs to class-III of pyridoxal-phosphate-dependent aminotransferases. | 0.513 |
vapB17 | argR | Rv2526 | Rv1657 | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Probable arginine repressor ArgR (AHRC); Regulates arginine biosynthesis genes. | 0.443 |
vapB17 | mazF8 | Rv2526 | Rv2274c | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible toxin MazF8; Putative toxic component of a type II toxin-antitoxin (TA) system, its cognate toxin is MaZE8. Probably an endoribonuclease (By similarity). | 0.511 |
vapB17 | vapB31 | Rv2526 | Rv0748 | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible antitoxin VapB31; Antitoxin component of a type II toxin-antitoxin (TA) system. Upon expression in M.smegmatis neutralizes the effect of cognate toxin VapC31. | 0.657 |
vapB17 | vapC10 | Rv2526 | Rv1397c | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible toxin VapC10; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB10 (By similarity). Belongs to the PINc/VapC protein family. | 0.625 |
vapB17 | vapC12 | Rv2526 | Rv1720c | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible toxin VapC12; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB12 (By similarity). Belongs to the PINc/VapC protein family. | 0.628 |
vapB17 | vapC17 | Rv2526 | Rv2527 | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible toxin VapC17; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. The cognate antitoxin is VapB17 (By similarity). Belongs to the PINc/VapC protein family. | 0.887 |
vapB17 | vapC3 | Rv2526 | Rv0549c | Possible antitoxin VapB17; Putative antitoxin component of a possible type II toxin- antitoxin (TA) system. The cognate toxin is VapC17. | Possible toxin VapC3; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits colony formation. Its toxic effect is neutralized by coexpression with cognate antitoxin VapB3. | 0.515 |