node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Rv0059 | vapC38 | Rv0059 | Rv2494 | Hypothetical protein; Rv0059, (MTV030.02), len: 230 aa. Hypothetical unknown protein. | Possible toxin VapC38. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase. Its cognate antitoxin is VapB38 (By similarity). | 0.487 |
Rv0059 | vapC40 | Rv0059 | Rv2596 | Hypothetical protein; Rv0059, (MTV030.02), len: 230 aa. Hypothetical unknown protein. | Possible toxin VapC40. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. | 0.575 |
Rv0059 | vapC47 | Rv0059 | Rv3408 | Hypothetical protein; Rv0059, (MTV030.02), len: 230 aa. Hypothetical unknown protein. | Possible toxin VapC47. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Upon expression in M.smegmatis inhibits translation and colony formation. Its toxic effect on colony formation is neutralized by coexpression with cognate antitoxin VapB47; the effect on translation has not been tested but is probably neutralized also.; Belongs to the PINc/VapC protein family. | 0.439 |
Rv2597 | Rv2598 | Rv2597 | Rv2598 | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | Rv2598, (MTCY227.03c), len: 164 aa. Conserved hypothetical protein, showing similarity with hypothetical proteins from Streptomyces coelicolor e.g. Q9X8S3|SCH10.34c (185 aa), FASTA scores: opt: 197, E(): 3.5e-06, (34.75% identity in 167 aa overlap); and Q9L088|SCC24.29c (172 aa),FASTA scores: opt: 149, E(): 0.0053, (37.65% identity in 146 aa overlap). Equivalent to AAK46988 from Mycobacterium tuberculosis strain CDC1551 (154 aa) but longer 10 aa. | 0.976 |
Rv2597 | ruvA | Rv2597 | Rv2593c | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.410 |
Rv2597 | vapB40 | Rv2597 | Rv2595 | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | 0.590 |
Rv2597 | vapC40 | Rv2597 | Rv2596 | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | Possible toxin VapC40. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. | 0.590 |
Rv2598 | Rv2597 | Rv2598 | Rv2597 | Rv2598, (MTCY227.03c), len: 164 aa. Conserved hypothetical protein, showing similarity with hypothetical proteins from Streptomyces coelicolor e.g. Q9X8S3|SCH10.34c (185 aa), FASTA scores: opt: 197, E(): 3.5e-06, (34.75% identity in 167 aa overlap); and Q9L088|SCC24.29c (172 aa),FASTA scores: opt: 149, E(): 0.0053, (37.65% identity in 146 aa overlap). Equivalent to AAK46988 from Mycobacterium tuberculosis strain CDC1551 (154 aa) but longer 10 aa. | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | 0.976 |
Rv2598 | vapB40 | Rv2598 | Rv2595 | Rv2598, (MTCY227.03c), len: 164 aa. Conserved hypothetical protein, showing similarity with hypothetical proteins from Streptomyces coelicolor e.g. Q9X8S3|SCH10.34c (185 aa), FASTA scores: opt: 197, E(): 3.5e-06, (34.75% identity in 167 aa overlap); and Q9L088|SCC24.29c (172 aa),FASTA scores: opt: 149, E(): 0.0053, (37.65% identity in 146 aa overlap). Equivalent to AAK46988 from Mycobacterium tuberculosis strain CDC1551 (154 aa) but longer 10 aa. | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | 0.584 |
Rv2598 | vapC40 | Rv2598 | Rv2596 | Rv2598, (MTCY227.03c), len: 164 aa. Conserved hypothetical protein, showing similarity with hypothetical proteins from Streptomyces coelicolor e.g. Q9X8S3|SCH10.34c (185 aa), FASTA scores: opt: 197, E(): 3.5e-06, (34.75% identity in 167 aa overlap); and Q9L088|SCC24.29c (172 aa),FASTA scores: opt: 149, E(): 0.0053, (37.65% identity in 146 aa overlap). Equivalent to AAK46988 from Mycobacterium tuberculosis strain CDC1551 (154 aa) but longer 10 aa. | Possible toxin VapC40. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. | 0.587 |
ruvA | Rv2597 | Rv2593c | Rv2597 | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | 0.410 |
ruvA | ruvB | Rv2593c | Rv2592c | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Probable holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | 0.999 |
ruvA | vapB40 | Rv2593c | Rv2595 | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | 0.554 |
ruvA | vapC40 | Rv2593c | Rv2596 | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | Possible toxin VapC40. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. | 0.572 |
ruvB | ruvA | Rv2592c | Rv2593c | Probable holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.999 |
ruvB | vapB40 | Rv2592c | Rv2595 | Probable holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | 0.553 |
ruvB | vapC40 | Rv2592c | Rv2596 | Probable holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. | Possible toxin VapC40. Contains PIN domain; Toxic component of a type II toxin-antitoxin (TA) system. An RNase (By similarity). Its cognate antitoxin is VapB40. | 0.572 |
vapB40 | Rv2597 | Rv2595 | Rv2597 | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | Probable membrane protein; Rv2597, (MTCY227.04c), len: 206 aa. Probable membrane protein. Predicted to be an outer membrane protein (See Song et al., 2008). | 0.590 |
vapB40 | Rv2598 | Rv2595 | Rv2598 | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | Rv2598, (MTCY227.03c), len: 164 aa. Conserved hypothetical protein, showing similarity with hypothetical proteins from Streptomyces coelicolor e.g. Q9X8S3|SCH10.34c (185 aa), FASTA scores: opt: 197, E(): 3.5e-06, (34.75% identity in 167 aa overlap); and Q9L088|SCC24.29c (172 aa),FASTA scores: opt: 149, E(): 0.0053, (37.65% identity in 146 aa overlap). Equivalent to AAK46988 from Mycobacterium tuberculosis strain CDC1551 (154 aa) but longer 10 aa. | 0.584 |
vapB40 | ruvA | Rv2595 | Rv2593c | Possible antitoxin VapB40; Antitoxin component of a type II toxin-antitoxin (TA) system. Its cognate toxin is VapC40. Upon expression in E.coli partially counteracts the ribonuclease activity of non-cognate toxins MazF6 and MazF9; Belongs to the VapB family. | Probable holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.554 |