node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PE27 | PPE43 | Rv2769c | Rv2768c | Rv2769c, (MTV002.34c), len: 275 aa. PE27, Member of the Mycobacterium tuberculosis PE family (see citation below), highly similar to many (notably in N-terminal part) e.g. P96361|Rv1040c|MTCY10G2.09 from Mycobacterium tuberculosis (275 aa), FASTA scores: opt: 1111, E(): 5.9e-52, (68.55% identity in 283 aa overlap). | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | 0.796 |
PE27 | Rv2767c | Rv2769c | Rv2767c | Rv2769c, (MTV002.34c), len: 275 aa. PE27, Member of the Mycobacterium tuberculosis PE family (see citation below), highly similar to many (notably in N-terminal part) e.g. P96361|Rv1040c|MTCY10G2.09 from Mycobacterium tuberculosis (275 aa), FASTA scores: opt: 1111, E(): 5.9e-52, (68.55% identity in 283 aa overlap). | Possible membrane protein; Rv2767c, (MTV002.32c), len: 117 aa (questionable ORF). Possible membrane protein, showing very weak similarity with Q9L2H7|SCC121.09 putative metal transport ABC transporter from Streptomyces coelicolor (256 aa),FASTA scores: opt: 110, E(): 1, (33.05% identity in 112 aa overlap). | 0.533 |
PE27 | Rv3778c | Rv2769c | Rv3778c | Rv2769c, (MTV002.34c), len: 275 aa. PE27, Member of the Mycobacterium tuberculosis PE family (see citation below), highly similar to many (notably in N-terminal part) e.g. P96361|Rv1040c|MTCY10G2.09 from Mycobacterium tuberculosis (275 aa), FASTA scores: opt: 1111, E(): 5.9e-52, (68.55% identity in 283 aa overlap). | Possible aminotransferase; Is essential for optimal growth; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | 0.681 |
PE27 | hddA | Rv2769c | Rv0115 | Rv2769c, (MTV002.34c), len: 275 aa. PE27, Member of the Mycobacterium tuberculosis PE family (see citation below), highly similar to many (notably in N-terminal part) e.g. P96361|Rv1040c|MTCY10G2.09 from Mycobacterium tuberculosis (275 aa), FASTA scores: opt: 1111, E(): 5.9e-52, (68.55% identity in 283 aa overlap). | Rv0115, (MTV031.09), len: 386 aa. Possible hddA,D-alpha-D-heptose-7-phosphate kinase (see citation below),similar to several hypothetical proteins and sugar kinases e.g. AAK27850.1|AF324836_3 D-glycero-D-manno-heptose 7-phosphate kinase from Aneurinibacillus thermoaerophilus (341 aa); AAK80995.1|AE007802_11 Sugar kinase from Clostridium acetobutylicum (364 aa). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.654 |
PE31 | PPE43 | Rv3477 | Rv2768c | Rv3477, (MTCY13E12.30), len: 98 aa. PE31, Member of the Mycobacterium tuberculosis PE family (see Brennan & Delogu 2002), similar to O53941|Rv1791|MTV049.13 (99 aa),FASTA scores: opt: 373, E(): 4.3e-18, (64.65% identity in 99 aa overlap); MTCI364.07; MTCY21C12.10c; MTCY1A11.25c; MTC1A11.04; MTCY359.33; etc. | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | 0.528 |
PE8 | PPE43 | Rv1040c | Rv2768c | Rv1040c, (MTCY10G2.09), len: 275 aa. PE8, Member of the Mycobacterium tuberculosis PE family (see citation below), most similar to AL008967|MTV002_34 Mycobacterium tuberculosis H37Rv (275 aa), FASTA scores: opt: 1111, E(): 0, (68.6% identity in 283 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | 0.907 |
PE8 | espG5 | Rv1040c | Rv1794 | Rv1040c, (MTCY10G2.09), len: 275 aa. PE8, Member of the Mycobacterium tuberculosis PE family (see citation below), most similar to AL008967|MTV002_34 Mycobacterium tuberculosis H37Rv (275 aa), FASTA scores: opt: 1111, E(): 0, (68.6% identity in 283 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Conserved protein; Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers. Belongs to the EspG family. | 0.898 |
PE8 | hddA | Rv1040c | Rv0115 | Rv1040c, (MTCY10G2.09), len: 275 aa. PE8, Member of the Mycobacterium tuberculosis PE family (see citation below), most similar to AL008967|MTV002_34 Mycobacterium tuberculosis H37Rv (275 aa), FASTA scores: opt: 1111, E(): 0, (68.6% identity in 283 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | Rv0115, (MTV031.09), len: 386 aa. Possible hddA,D-alpha-D-heptose-7-phosphate kinase (see citation below),similar to several hypothetical proteins and sugar kinases e.g. AAK27850.1|AF324836_3 D-glycero-D-manno-heptose 7-phosphate kinase from Aneurinibacillus thermoaerophilus (341 aa); AAK80995.1|AE007802_11 Sugar kinase from Clostridium acetobutylicum (364 aa). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.410 |
PPE43 | PE27 | Rv2768c | Rv2769c | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Rv2769c, (MTV002.34c), len: 275 aa. PE27, Member of the Mycobacterium tuberculosis PE family (see citation below), highly similar to many (notably in N-terminal part) e.g. P96361|Rv1040c|MTCY10G2.09 from Mycobacterium tuberculosis (275 aa), FASTA scores: opt: 1111, E(): 5.9e-52, (68.55% identity in 283 aa overlap). | 0.796 |
PPE43 | PE31 | Rv2768c | Rv3477 | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Rv3477, (MTCY13E12.30), len: 98 aa. PE31, Member of the Mycobacterium tuberculosis PE family (see Brennan & Delogu 2002), similar to O53941|Rv1791|MTV049.13 (99 aa),FASTA scores: opt: 373, E(): 4.3e-18, (64.65% identity in 99 aa overlap); MTCI364.07; MTCY21C12.10c; MTCY1A11.25c; MTC1A11.04; MTCY359.33; etc. | 0.528 |
PPE43 | PE8 | Rv2768c | Rv1040c | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Rv1040c, (MTCY10G2.09), len: 275 aa. PE8, Member of the Mycobacterium tuberculosis PE family (see citation below), most similar to AL008967|MTV002_34 Mycobacterium tuberculosis H37Rv (275 aa), FASTA scores: opt: 1111, E(): 0, (68.6% identity in 283 aa overlap). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.907 |
PPE43 | Rv1535 | Rv2768c | Rv1535 | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Unknown protein; Rv1535, (MTCY07A7A.04), len: 78 aa. Unknown protein. | 0.657 |
PPE43 | Rv2767c | Rv2768c | Rv2767c | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Possible membrane protein; Rv2767c, (MTV002.32c), len: 117 aa (questionable ORF). Possible membrane protein, showing very weak similarity with Q9L2H7|SCC121.09 putative metal transport ABC transporter from Streptomyces coelicolor (256 aa),FASTA scores: opt: 110, E(): 1, (33.05% identity in 112 aa overlap). | 0.922 |
PPE43 | Rv3778c | Rv2768c | Rv3778c | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Possible aminotransferase; Is essential for optimal growth; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. | 0.728 |
PPE43 | espG5 | Rv2768c | Rv1794 | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Conserved protein; Specific chaperone for cognate PE/PPE proteins. Plays an important role in preventing aggregation of PE/PPE dimers. Belongs to the EspG family. | 0.891 |
PPE43 | gabT | Rv2768c | Rv2589 | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | 4-aminobutyrate aminotransferase; Rv2589, (MTCY227.12c), len: 449 aa. Probable gabT,4-aminobutyrate aminotransferase, equivalent to P40829|GABT_MYCLE|ML0485|MLCB1259.03c|B1177_F2_67 4-aminobutyrate aminotransferase (446 aa), FASTA scores: opt: 2468, E(): 4.5e-141, (83.75% identity in 449 aa overlap). Also highly similar to others e.g. O86823|GABT from Streptomyces coelicolor (444 aa), FASTA scores: opt: 1832, E(): 8e-103, (63.9% identity in 443 aa overlap); AAK79395|CAC1427 from Clostridium acetobutylicum (445 aa),FASTA scores: opt: 1283, E(): 8.4e-70, (45.75% identity in 433 aa overla [...] | 0.860 |
PPE43 | hddA | Rv2768c | Rv0115 | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Rv0115, (MTV031.09), len: 386 aa. Possible hddA,D-alpha-D-heptose-7-phosphate kinase (see citation below),similar to several hypothetical proteins and sugar kinases e.g. AAK27850.1|AF324836_3 D-glycero-D-manno-heptose 7-phosphate kinase from Aneurinibacillus thermoaerophilus (341 aa); AAK80995.1|AE007802_11 Sugar kinase from Clostridium acetobutylicum (364 aa). This region is a possible MT-complex-specific genomic island (See Becq et al., 2007). | 0.659 |
PPE43 | yajC | Rv2768c | Rv2588c | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | Probable conserved membrane protein secretion factor YajC; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.698 |
Rv1535 | PPE43 | Rv1535 | Rv2768c | Unknown protein; Rv1535, (MTCY07A7A.04), len: 78 aa. Unknown protein. | Rv2768c, (MTV002.33c), len: 394 aa. PPE43, Member of the Mycobacterium tuberculosis PPE family, highly similar to many e.g. upstream ORF O33312|Rv2770c|MTV002.35c (402 aa), FASTA scores: opt: 1135, E(): 6.1e-51, (62.15% identity in 391 aa overlap); and P96362|Rv1039c|MTCY10G2.10 from M. tuberculosis (391 aa), FASTA scores: opt: 1721,E(): 6.8e-81, (70.35% identity in 398 aa overlap). Equivalent to AAK47157 from Mycobacterium tuberculosis strain CDC1551 (462 aa) but shorter 68 aa. | 0.657 |
Rv1535 | gabT | Rv1535 | Rv2589 | Unknown protein; Rv1535, (MTCY07A7A.04), len: 78 aa. Unknown protein. | 4-aminobutyrate aminotransferase; Rv2589, (MTCY227.12c), len: 449 aa. Probable gabT,4-aminobutyrate aminotransferase, equivalent to P40829|GABT_MYCLE|ML0485|MLCB1259.03c|B1177_F2_67 4-aminobutyrate aminotransferase (446 aa), FASTA scores: opt: 2468, E(): 4.5e-141, (83.75% identity in 449 aa overlap). Also highly similar to others e.g. O86823|GABT from Streptomyces coelicolor (444 aa), FASTA scores: opt: 1832, E(): 8e-103, (63.9% identity in 443 aa overlap); AAK79395|CAC1427 from Clostridium acetobutylicum (445 aa),FASTA scores: opt: 1283, E(): 8.4e-70, (45.75% identity in 433 aa overla [...] | 0.653 |